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My CartReactivity：Human
Application：FCM
Clone Type：Monoclonal Antibody
Storage：Store at 4℃ in dark.Do not freeze.
Gene ID：6965
Host：Mouse
Qty：
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| Name | Anti-TCR γ/δ(PE) Monoclonal Antibody |
| Host | Mouse |
| Clone Type | Monoclonal Antibody |
| Subtype | IgG1，κ |
| Dilution Ratio | FCM 5uL/Test. |
| Target | TCR γ/δ |
| Background | T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface of antigen presenting cells (APC). Each T cell receptor is a dimer consisting of one alpha and one beta chain or one delta and one gamma chain. In a single cell，the T cell receptor loci are rearranged and expressed in the order delta，gamma，beta，and alpha. If both delta and gamma rearrangements produce functional chains，the cell expresses delta and gamma. If not，the cell proceeds to rearrange the beta and alpha loci. This region represents the germline organization of the T cell receptor gamma locus. The gamma locus includes V (variable) ，J (joining)，and C (constant) segments. During T cell development，the gamma chain is synthesized by a recombination event at the DNA level joining a V segment with a J segment; the C segment is later joined by splicing at the RNA level. Recombination of many different V segments with several J segments provides a wide range of antigen recognition. Additional diversity is attained by junctional diversity，resulting from the random additional of nucleotides by terminal deoxynucleotidyltransferase. Several V segments of the gamma locus are known to be incapable of encoding a protein and are considered pseudogenes. Somatic rearrangment of the gamma locus has been observed in T cells derived from patients with T cell leukemia and ataxia telangiectasia. |
| Swiss Prot | P03986 |
| Gene ID | 6965 |
| Subcellular Location | Cell membrane |
| Storage | Store at 4℃ in dark.Do not freeze. |
| Unit | Piece |
| Specification | 25T 100T |
| Reactivity | Human |
| Application | FCM |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Kindly reminder：Quick spin before use. If you have any questions, please contact us.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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