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My CartReactivity：Mouse,Human
Application：IHC,WB
Clone Type：Polyclonal Antibody
Storage：Store at -20℃. Avoid freeze / thaw cycles.
Gene ID：80380
Host：Rabbit
Qty：
Size：
| Name | Anti-PDCD1LG2 Polyclonal Antibody |
| Host | Rabbit |
| Clone Type | Polyclonal Antibody |
| Subtype | IgG |
| Dilution Ratio | WB 1:1000-3000.IHC 1:50-200. |
| Target | PDCD1LG2 |
| Background | Programmed Death Ligand 2 (PD-L2); also known as B7-DC and butyrophilin-like protein; is a member of the B7 family of proteins that provide signals for regulating T-cell activation and tolerance .PD-L2 is expressed on dendritic cells; subsets of activated CD4+ and CD8+ T cells; and memory B cells that differentiate into plasma cells. At inflammatory sites such as rheumatoid arthritis; allergen exposure; and virus infection; PD-L2 is up-regulated on synoviocytes; infiltrating macrophages; dendritic cells; and airway epithelial cells. PD-L2; along with B7-H1/PD-L1; binds to T cell PD-1 where it promotes IFN-gamma production and CD40 Ligand up-regulation while inhibiting IL-4 production. In addition; PD-L2 binds to RGM-B on macrophages and alveolar epithelial cells; supporting respiratory immune tolerance. In asthma; PD-L2 suppresses IL-5 and IL-13 production; promotes IL-12 production by dendritic cells; and supports allergen-induced airway hyper-responsiveness and mucus production. |
| Swiss Prot | Q9BQ51 |
| Gene ID | 80380 |
| Subcellular Location | Cell membrane Secreted |
| Immunogen | A synthetic peptide of human PDCD1LG2 |
| Public Immunogen Range | 150-200/273aa |
| Calculated MW | 21/31kDa |
| Observed MW | 50kDa |
| Purification Method | Affinity purification |
| Storage Buffer | PBS with 50% Glycerol, 0.03% Proclin300, 0.5% BSA, pH 7.3. |
| Storage | Store at -20℃. Avoid freeze / thaw cycles. |
| Unit | 支 |
| Specification | 20ul 50ul 100ul |
| Reactivity | Human Mouse |
| Application | WB IHC |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Kindly reminder：Quick spin before use. If you have any questions, please contact us.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
Western blot analysis with PDCD1LG2 antibody diluted at 1:2000;Lane: MG63.
Immunohistochemistry of paraffin-embedded Human prostate cancer with PDCD1LG2 antibody diluted at 1:100.
Immunohistochemistry of paraffin-embedded Human liver cancer with PDCD1LG2 antibody diluted at 1:100.
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