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My CartReactivity：Human,Mouse
Application：WB,IHC
Clone Type：Polyclonal Antibody
Storage：Store at -20℃. Avoid freeze / thaw cycles.
Gene ID：64834
Host：Rabbit
Qty：
Size：
| Name | Anti-ELOVL1 Polyclonal Antibody |
| Host | Rabbit |
| Clone Type | Polyclonal Antibody |
| Subtype | IgG |
| Predicted Reactivity | Cow;Rat;Dog;Rabbit |
| Dilution Ratio | WB 1:1000-3000.IHC 1:50-200. |
| Target | ELOVL1 |
| Background | Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle (PubMed:29496980，PubMed:30487246).This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that exhibits activity toward saturated and monounsaturated acyl-CoA substrates，with the highest activity towards C22:0 acyl-CoA. May participate in the production of both saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators. Important for saturated C24:0 and monounsaturated C24:1 sphingolipid synthesis (PubMed:20937905).Indirectly inhibits RPE65 via production of VLCFAs. |
| Swiss Prot | Q9BW60 |
| Gene ID | 64834 |
| Subcellular Location | Cytoplasm Nucleus |
| Immunogen | A synthetic peptide of human ELOVL1 |
| Public Immunogen Range | 70-120/279aa |
| Calculated MW | 29/33kDa |
| Observed MW | 33kDa |
| Purification Method | Affinity purification |
| Storage Buffer | PBS with 50% Glycerol，0.03% Proclin300，0.5% BSA，pH 7.3. |
| Storage | Store at -20℃. Avoid freeze / thaw cycles. |
| Unit | bottle |
| Specification | 20ul 50ul 100ul |
| Reactivity | Human Mouse |
| Application | WB IHC |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Kindly reminder：Quick spin before use. If you have any questions, please contact us.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
Western blot analysis with ELOVL1 antibody diluted at 1:2000;Lane: HeLa,293T,SW480,SKOV3,Jurkat.
Immunohistochemistry of paraffin-embedded Human stomach cancer with ELOVL1 antibody diluted at 1:100.
Immunohistochemistry of paraffin-embedded Human colorectal cancer with ELOVL1 antibody diluted at 1:100.
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