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My CartReactivity：Human,Rat,Mouse
Application：IHC
Clone Type：Polyclonal Antibody
Storage：Store at -20℃. Avoid freeze / thaw cycles.
Gene ID：10587
Host：Rabbit
Qty：
Size：
| Name | Anti-TXNRD2 Polyclonal Antibody |
| Host | Rabbit |
| Clone Type | Polyclonal Antibody |
| Subtype | IgG |
| Predicted Reactivity | Bovine |
| Dilution Ratio | IHC 1:50-200. |
| Target | TXNRD2 |
| Background | The protein encoded by this gene belongs to the pyridine nucleotide-disulfide oxidoreductase family; and is a member of the thioredoxin (Trx) system. Three thioredoxin reductase (TrxR) isozymes are found in mammals. TrxRs are selenocysteine-containing flavoenzymes; which reduce thioredoxins; as well as other substrates; and play a key role in redox homoeostasis. This gene encodes a mitochondrial form important for scavenging reactive oxygen species in mitochondria. It functions as a homodimer containing FAD; and selenocysteine (Sec) at the active site. Sec is encoded by UGA codon that normally signals translation termination. The 3’ UTRs of selenoprotein mRNAs contain a conserved stem-loop structure; the Sec insertion sequence (SECIS) element; which is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Alternatively spliced transcript variants encoding different isoforms; including a few localized in the cytosol and some lacking the C-terminal Sec residue; have been found for this gene. |
| Swiss Prot | Q9NNW7 |
| Gene ID | 10587 |
| Subcellular Location | Cytoplasm |
| Immunogen | Recombinant protein of human TXNRD2 |
| Public Immunogen Range | 10-300aa |
| Calculated MW | 30/47/54/57kDa |
| Purification Method | Affinity purification |
| Storage Buffer | PBS with 50% Glycerol，0.03% Proclin300，0.5% BSA，pH 7.3. |
| Storage | Store at -20℃. Avoid freeze / thaw cycles. |
| Unit | bottle |
| Specification | 20ul 50ul 100ul |
| Reactivity | Human Mouse Rat |
| Application | IHC |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Kindly reminder：Quick spin before use. If you have any questions, please contact us.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
Immunohistochemistry of paraffin-embedded Human colorectal cancer with TXNRD2 antibody diluted at 1:100.
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