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My CartStorage：Store at -20℃，2 years.Avoid freeze/thaw cycles.
Appearance：Lyophilized powder
Gene ID：3098
Application：Blocking Peptide of K111516P Antibody
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| Name | HK1 Antibody Blocking Peptide |
| Appearance | Lyophilized powder |
| Storage | Store at -20℃，2 years.Avoid freeze/thaw cycles. |
| Swiss Prot | P19367 |
| Gene ID | 3098 |
| Background | Catalyzes the phosphorylation of various hexoses， such as D-glucose， D-glucosamine， D-fructose， D-mannose and 2-deoxy-D-glucose， to hexose 6-phosphate (D-glucose 6-phosphate， D-glucosamine 6-phosphate， D-fructose 6-phosphate， D-mannose 6-phosphate and 2-deoxy-D-glucose 6-phosphate， respectively) (PubMed:1637300， PubMed:25316723， PubMed:27374331). Does not phosphorylate N-acetyl-D-glucosamine (PubMed:27374331). Mediates the initial step of glycolysis by catalyzing phosphorylation of D-glucose to D-glucose 6-phosphate (By similarity). Involved in innate immunity and inflammation by acting as a pattern recognition receptor for bacterial peptidoglycan (PubMed:27374331). When released in the cytosol， N-acetyl-D-glucosamine component of bacterial peptidoglycan inhibits the hexokinase activity of HK1 and causes its dissociation from mitochondrial outer membrane， thereby activating the NLRP3 inflammasome (PubMed:27374331). |
| Application | Blocking Peptide of K111516P Antibody |
| Source | Synthetic |
| Purification Method | HPLC |
| Biological Activity | Not tested |
| Unit | Piece |
| Specification | 500ug |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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