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My CartStorage：Store at -20℃，2 years.Avoid freeze/thaw cycles.
Appearance：Lyophilized powder
Gene ID：51234
Application：Blocking Peptide of K113150P Antibody
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| Name | EMC4 Antibody Blocking Peptide |
| Appearance | Lyophilized powder |
| Storage | Store at -20℃，2 years.Avoid freeze/thaw cycles. |
| Swiss Prot | Q5J8M3 |
| Gene ID | 51234 |
| Interval Range | 20-70/183aa |
| Background | Part of the endoplasmic reticulum membrane protein complex (EMC) that enables the energy-independent insertion into endoplasmic reticulum membranes of newly synthesized membrane proteins (PubMed:30415835， PubMed:29809151， PubMed:29242231， PubMed:32459176， PubMed:32439656).Preferentially accommodates proteins with transmembrane domains that are weakly hydrophobic or contain destabilizing features such as charged and aromatic residues (PubMed:30415835， PubMed:29809151， PubMed:29242231).Involved in the cotranslational insertion of multi-pass membrane proteins in which stop-transfer membrane-anchor sequences become ER membrane spanning helices (PubMed:30415835， PubMed:29809151).It is also required for the post-translational insertion of tail-anchored/TA proteins in endoplasmic reticulum membranes (PubMed:29809151， PubMed:29242231).By mediating the proper cotranslational insertion of N-terminal transmembrane domains in an N-exo topology， with translocated N-terminus in the lumen of the ER， controls the topology of multi-pass membrane proteins like the G protein-coupled receptors (PubMed:30415835).By regulating the insertion of various proteins in membranes， it is indirectly involved in many cellular processes (Probable). |
| Application | Blocking Peptide of K113150P Antibody |
| Source | Synthetic |
| Purification Method | HPLC |
| Biological Activity | Not tested |
| Unit | Piece |
| Specification | 500ug |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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