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My CartReactivity：Mouse,Rat,Human
Application：IHC
Clone Type：Polyclonal Antibody
Storage：Store at -20℃. Avoid freeze / thaw cycles.
Gene ID：5788
Host：Rabbit
Qty：
Size：
| Name | Anti-PTPRC Polyclonal Antibody |
| Host | Rabbit |
| Clone Type | Polyclonal Antibody |
| Subtype | IgG |
| Dilution Ratio | IHC 1:50-200. |
| Target | PTPRC |
| Background | The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth，differentiation，mitosis，and oncogenic transformation. This PTP contains an extracellular domain，a single transmembrane segment and two tandem intracytoplasmic catalytic domains，and thus is classified as a receptor type PTP. This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes，or by activating various Src family kinases required for the antigen receptor signaling. This PTP also suppresses JAK kinases，and thus functions as a regulator of cytokine receptor signaling. Alternatively spliced transcripts variants of this gene，which encode distinct isoforms，have been reported. |
| Swiss Prot | P08575 |
| Gene ID | 5788 |
| Subcellular Location | Cell membrane Cytoplasm |
| Immunogen | A synthetic peptide of human PTPRC |
| Public Immunogen Range | 800-850/1306aa |
| Calculated MW | 131/136/138/141/143/147kDa |
| Purification Method | Octanoic acid-ammonium sulfate precipitation |
| Storage Buffer | PBS with 50% Glycerol，0.03% Proclin300，0.5% BSA，pH 7.3. |
| Storage | Store at -20℃. Avoid freeze / thaw cycles. |
| Unit | bottle |
| Specification | 20ul 50ul 100ul |
| Reactivity | Human Mouse Rat |
| Application | IHC |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Kindly reminder：Quick spin before use. If you have any questions, please contact us.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
Immunohistochemistry of paraffin-embedded Human liver cancer with PTPRC antibody diluted at 1:100.
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