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My CartReactivity：Rat,Human,Mouse
Application：IHC
Clone Type：Polyclonal Antibody
Storage：Store at -20℃. Avoid freeze / thaw cycles.
Gene ID：4893
Host：Rabbit
Qty：
Size：
| Name | Anti-NRAS Polyclonal Antibody |
| Host | Rabbit |
| Clone Type | Polyclonal Antibody |
| Subtype | IgG |
| Predicted Reactivity | Chimpanzee;Pig;Chicken;Guinea pig;Opossums |
| Dilution Ratio | IHC 1:50-200. |
| Target | NRAS |
| Background | This is an N-ras oncogene encoding a membrane protein that shuttles between the Golgi apparatus and the plasma membrane. This shuttling is regulated through palmitoylation and depalmitoylation by the ZDHHC9-GOLGA7 complex. The encoded protein，which has intrinsic GTPase activity，is activated by a guanine nucleotide-exchange factor and inactivated by a GTPase activating protein. Mutations in this gene have been associated with somatic rectal cancer，follicular thyroid cancer，autoimmune lymphoproliferative syndrome，Noonan syndrome，and juvenile myelomonocytic leukemia. |
| Swiss Prot | P01111 |
| Gene ID | 4893 |
| Subcellular Location | Cell membraneCytoplasm Secreted |
| Immunogen | A synthetic peptide of human NRAS |
| Public Immunogen Range | 100-150/189aa |
| Calculated MW | 21kDa |
| Purification Method | Octanoic acid-ammonium sulfate precipitation |
| Storage Buffer | PBS with 50% Glycerol，0.03% Proclin300，0.5% BSA，pH 7.3. |
| Storage | Store at -20℃. Avoid freeze / thaw cycles. |
| Unit | bottle |
| Specification | 20ul 50ul 100ul |
| Reactivity | Human Mouse Rat |
| Application | IHC |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Kindly reminder：Quick spin before use. If you have any questions, please contact us.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
Immunohistochemistry of paraffin-embedded Human colorectal cancer with NRAS antibody diluted at 1:100.
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