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My CartReactivity：Mouse,Rat,Human
Application：IHC
Clone Type：Polyclonal Antibody
Storage：Store at -20℃. Avoid freeze / thaw cycles.
Gene ID：1030
Host：Rabbit
Qty：
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| Name | Anti-CDKN2B Polyclonal Antibody |
| Host | Rabbit |
| Clone Type | Polyclonal Antibody |
| Subtype | IgG |
| Predicted Reactivity | Bovine |
| Dilution Ratio | IHC 1:50-200. |
| Target | CDKN2B |
| Background | This gene lies adjacent to the tumor suppressor gene CDKN2A in a region that is frequently mutated and deleted in a wide variety of tumors. This gene encodes a cyclin-dependent kinase inhibitor，which forms a complex with CDK4 or CDK6，and prevents the activation of the CDK kinases，thus the encoded protein functions as a cell growth regulator that controls cell cycle G1 progression. The expression of this gene was found to be dramatically induced by TGF beta，which suggested its role in the TGF beta induced growth inhibition. Two alternatively spliced transcript variants of this gene，which encode distinct proteins，have been reported. |
| Swiss Prot | P42772 |
| Gene ID | 1030 |
| Subcellular Location | Cytoplasm |
| Immunogen | Recombinant protein of human CDKN2B |
| Public Immunogen Range | 1-138aa |
| Calculated MW | 8/15kDa |
| Purification Method | Affinity purification |
| Storage Buffer | PBS with 50% Glycerol，0.03% Proclin300，0.5% BSA，pH 7.3. |
| Storage | Store at -20℃. Avoid freeze / thaw cycles. |
| Unit | bottle |
| Specification | 20ul 50ul 100ul |
| Reactivity | Human Mouse Rat |
| Application | IHC |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Kindly reminder：Quick spin before use. If you have any questions, please contact us.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
Immunohistochemistry of paraffin-embedded Human liver cancer with CDKN2B antibody diluted at 1:100.
Immunohistochemistry of paraffin-embedded Human thyroid cancer with CDKN2B antibody diluted at 1:100.
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