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My Cart> Cell Biology > Cell Detection > Cell Growth Factor > Recombinant Human Sclerostin/SOSTPurity：≥95% as determined by reducing SDS-PAGE.
Storage：Powder:＜-20℃ for long store;RT，3 weeks.Liquid:4-7℃，2-7 days;＜-20℃，3 months.
Appearance：Lyophilized from a 0.2 μm filtered solution of 20mM Tris, 250mM NaCl, pH 8.0.
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| Appearance | Lyophilized from a 0.2 μm filtered solution of 20mM Tris, 250mM NaCl, pH 8.0. |
| Purity | ≥95% as determined by reducing SDS-PAGE. |
| Storage | Powder:＜-20℃ for long store;RT，3 weeks.Liquid:4-7℃，2-7 days;＜-20℃，3 months. |
| Transport Condition | The product is shipped at ambient temperature. |
| Background | Sclerostin，also known as SOST，is a member of the Cerberus/DAN family of BMP antagonists.SOST is asecreted glycoprotein with a C-terminal cysteine knot-like (CTCK) domain.It shows sequence similarity to the DAN (differential screening-selected gene aberrative in neuroblastoma) family of bone morphogenetic protein (BMP) antagonists.SOST is produced by the osteocyte and has anti-anabolic effects on bone formation.It is a negative regulator of bone growth that acts through inhibition of Wnt signaling and bone formation. |
| Source | Human cells |
| Solvent | Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 μg/ml. Dissolve the lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| Endotoxin | Less than 0.1 ng/ug(1 IEU/ug)as determined by LAL test. |
| Unit | Piece |
| Specification | 10ug 50ug 500ug 1mg |
Recombinant Human Sclerostin is produced by our Mammalian expression system and the target gene encoding Gln24-Tyr213 is expressed with a 6His tag at the C-terminus.
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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