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My Cart> Cell Biology > Cell Detection > Cell Growth Factor > Recombinant Human R-spondin-1/RSPO1Purity：≥95% as determined by reducing SDS-PAGE.
Storage：Powder:＜-20℃ for long store;RT，3 weeks.Liquid:4-7℃，2-7 days;＜-20℃，3 months.
Appearance：Lyophilized from a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, pH 8.0.
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| Appearance | Lyophilized from a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, pH 8.0. |
| Purity | ≥95% as determined by reducing SDS-PAGE. |
| Storage | Powder:＜-20℃ for long store;RT，3 weeks.Liquid:4-7℃，2-7 days;＜-20℃，3 months. |
| Transport Condition | The product is shipped at ambient temperature.Upon receipt，store it immediately at the temperature listed below. |
| Background | RSPO1 is a secreted protein，containing 2 FU(furin-like) repeats and 1 TSP type-1 domain and belonging to the R-spondin family.RSPO1 is required for the early development of gonads，regardless of sex.It has been found in mice only eleven days after fertilization.To induce cell proliferation，it acts synergistically with WNT4.They help stabilize β catenin，which activates downstream targets.RSPO1 is necessary in female sex development.It augments the WNT/β catenin pathway to oppose male sex development.In critical gonadal stages，between six and nine weeks after fertilization，the ovaries upregulate it while the testes downregulate it.RSPO1 can potentially aid in the treatment of mucositis，which is characterized by inflammation of the oral cavity.This unfortunate condition often accompanies chemotherapy and radiation in cancer patients with head and neck tumors. |
| Source | Human cells |
| Solvent | Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| Endotoxin | Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test. |
| Unit | Piece |
| Specification | 10ug 50ug 500ug 1mg |
Recombinant Human R-spondin-1 is produced by our Mammalian expression system and the target gene encoding Arg31-Ala263 is expressed with a 6His tag at the C-terminus.
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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