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My CartStorage：Store at -20°C. Avoid freeze / thaw cycles.
Appearance：Lyophilized powder
Gene ID：2064
Application：Blocking Peptide of K115103P Antibody
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| Name | ERBB2 Antibody Blocking Peptide |
| Appearance | Lyophilized powder |
| Storage | Store at -20°C. Avoid freeze / thaw cycles. |
| Swiss Prot | P04626 |
| Gene ID | 2064 |
| Interval Range | 1180-1230/1255aa |
| Background | This gene encodes a member of the epidermal growth factor (EGF) receptor family of receptor tyrosine kinases. This protein has no ligand binding domain of its own and therefore cannot bind growth factors. However， it does bind tightly to other ligand-bound EGF receptor family members to form a heterodimer， stabilizing ligand binding and enhancing kinase-mediated activation of downstream signalling pathways， such as those involving mitogen-activated protein kinase and phosphatidylinositol-3 kinase. Allelic variations at amino acid positions 654 and 655 of isoform a (positions 624 and 625 of isoform b) have been reported， with the most common allele， Ile654/Ile655， shown here. Amplification and/or overexpression of this gene has been reported in numerous cancers， including breast and ovarian tumors. Alternative splicing results in several additional transcript variants， some encoding different isoforms and others that have not been fully characterized. |
| Application | Blocking Peptide of K115103P Antibody |
| Source | Synthetic |
| Purification Method | HPLC |
| Biological Activity | Not tested |
| Unit | Piece |
| Specification | 500ug |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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