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My CartReactivity：Mouse,Human,Human;Mouse
Application：IHC
Clone Type：Polyclonal Antibody
Storage：Store at -20℃. Avoid freeze / thaw cycles.
Gene ID：1308
Host：Rabbit
Qty：
Size：
| Name | Anti-COL17A1 Polyclonal Antibody |
| Host | Rabbit |
| Clone Type | Polyclonal Antibody |
| Subtype | IgG |
| Predicted Reactivity | Bovine;Chicken |
| Dilution Ratio | IHC 1:50-200. |
| Target | COL17A1 |
| Background | This gene encodes the alpha chain of type XVII collagen. Unlike most collagens，collagen XVII is a transmembrane protein. Collagen XVII is a structural component of hemidesmosomes，multiprotein complexes at the dermal-epidermal basement membrane zone that mediate adhesion of keratinocytes to the underlying membrane. Mutations in this gene are associated with both generalized atrophic benign and junctional epidermolysis bullosa. Two homotrimeric forms of type XVII collagen exist. The full length form is the transmembrane protein. A soluble form，referred to as either ectodomain or LAD-1，is generated by proteolytic processing of the full length form. |
| Swiss Prot | Q9UMD9 |
| Gene ID | 1308 |
| Subcellular Location | Cytoplasm Cell membrane |
| Immunogen | Recombinant protein of human COL17A1 |
| Public Immunogen Range | 1-170aa |
| Calculated MW | 142/151kDa |
| Purification Method | Affinity purification |
| Storage Buffer | PBS with 50% Glycerol，0.03% Proclin300，0.5% BSA，pH 7.3. |
| Storage | Store at -20℃. Avoid freeze / thaw cycles. |
| Unit | bottle |
| Specification | 20ul 50ul 100ul |
| Reactivity | Human;Mouse Mouse Human |
| Application | IHC |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Kindly reminder：Quick spin before use. If you have any questions, please contact us.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
Immunohistochemistry of paraffin-embedded Human pancreatic cancer with COL17A1 antibody diluted at 1:100.
Immunohistochemistry of paraffin-embedded Human skin cancer with COL17A1 antibody diluted at 1:100.
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