Inauhzin
Cat.No:II4650 Solarbio
CAS:309271-94-1
Purity:HPLC≥98%
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Purity:HPLC≥98%
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Size:
CAS | 309271-94-1 |
Name | Inauhzin |
Purity | HPLC≥98% |
Target Point | Sirtuin |
Passage | Cell Cycle;DNA Damage/DNA Repair; Epigenetics |
Background | Inauhzin is a SIRT1 inhibitor with cell permeability that reactivates p53 by inhibiting SIRT1 deacetylation activity. |
Biological Activity | Inauhzin is a dual SirT1/IMPDH2 inhibitor, and acts as an activator p53, used in the research of cancer.[1-3] |
Data Literature Source | [1]. Zhang Q, et al. A small molecule Inauhzin inhibits SIRT1 activity and suppresses tumour growth through activation of p53. EMBO Mol Med. 2012 Apr;4(4):298-312. [2]. Zhang Y, et al. Inauhzin and Nutlin3 synergistically activate p53 and suppress tumor growth. Cancer Biol Ther. 2012 Aug;13(10):915-24. [3]. Nguyen D, et al. Reviving the guardian of the genome: Small molecule activators of p53. Pharmacol Ther. 2017 Oct;178:92-108. |
Unit | Bottle |
Specification | 10mg |
Remark:These protocols are for reference only. Solarbio does not independently validate these methods.
Note:
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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