SW480
Cat.No：SCC-110716 Solarbio
Storage：Store at -70℃
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Secondary Antibodies
SAlexa Fluor-Conjugated
Other Fluorescent-Conjugated
Other-Conjugated
Colloidal Gold Reagent
Alkaline Phosphatase(AP)-Conjugated
Colloidal Gold-Conjugated
FITC-Conjugated
Biotin-Conjugated
Purified Secondary Antibodies
Allophycocyanin(APC)-Conjugated
CY Fluorescent-Conjugated
Phycoglobin(PE)-Conjugated
RBTIC-Conjugated
Peroxidase (HRP)-Conjugated
Secondary Antibodies
SAlexa Fluor-Conjugated
Other Fluorescent-Conjugated
Other-Conjugated
Colloidal Gold Reagent
Alkaline Phosphatase(AP)-Conjugated
Colloidal Gold-Conjugated
FITC-Conjugated
Biotin-Conjugated
Purified Secondary Antibodies
Allophycocyanin(APC)-Conjugated
CY Fluorescent-Conjugated
Phycoglobin(PE)-Conjugated
RBTIC-Conjugated
Peroxidase (HRP)-Conjugated
Inhibitors & Antagonists & Agonists
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Endocrinology & Hormones
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HIF
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GPCR & G Protein
Neuronal Signal Pathway
MAPK
NF-κB
Membrane Transporter & Ion Channel
TGF-β/Smad
Hippo
Antibody-drug Conjugate/ADC Related
Others
Inhibitors & Antagonists & Agonists
PI3K/Akt/mTOR
Endocrinology & Hormones
Protein Tyrosine Kinase/PTK
Angiogenesis
HIF
Immunology & Inflammation
Stem Cells
Apoptosis
Metabolic Enzyme & Protease
Autophagy
ER Stress
Cell Cycle
Cytoskeleton
DNA Damage & DNA Repai
Epigenetics
Ubiquitin
JAK/STAT
GPCR & G Protein
Neuronal Signal Pathway
MAPK
NF-κB
Membrane Transporter & Ion Channel
TGF-β/Smad
Hippo
Antibody-drug Conjugate/ADC Related
Others
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Pipette & Dispenser & Pipette Dispensing Instrument
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Temperature Control & Sampling & Grinding Crushing Instrument
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Spectrophotometer
Centrifuge
Shaker
Vacuum Pump
Other Small Instruments
Instruments
Pipette & Dispenser & Pipette Dispensing Instrument
Oscillating Mixing & Stirring & Dispersing Instrument
Temperature Control & Sampling & Grinding Crushing Instrument
Sterilization & Filtration Instruments
PCR Instrument & Light Glue Instrument
Spectrophotometer
Centrifuge
Shaker
Vacuum Pump
Other Small Instruments
Product Information
| Name | SW480 |
| Full Name | Human colon cancer cell |
| Storage | Store at -70℃ |
| Transport Condition | Dry ice transport |
| Culture Condition | Leibovitz's L-15＋10% FBS＋1% P/S |
| Cell Type | Adherent cell |
| Background | SW480 [SW-480] cells were derived from rectal adenocarcinoma in situ, and SW620 cells were derived from lymph node metastasis one year later in the same patient. CSAp and rectal antibody 3 negative; Keratin immunoperoxidase staining was positive. G→A mutation in the 273rd codon of p53 gene leads to Arg→His substitution, and C→T mutation in the 309th codon leads to Pro→Ser substitution. The expression level of p53 protein was increased, and the expressions of oncogenes c-myc, K-ras, H-ras, N-ras, myb, sis and fos were positive, while the expression of oncogene N-myc was not detected. SW480 [SW-480] cells do not express cytolytic enzyme, a metalloproteinase associated with tumor invasion. It has been reported that SW480 [SW-480] cells express GM-CSF. SW480 [SW-480] cells have a mutation in the 12-bit codon of ras proto-oncogene, which can be used as a positive control for PCR detection of this mutation. It was passed down to the 91st generation when A. Leibovitz submitted it to the ATCC in November 1978. |
| Source | Rectum;Colorectal adenocarcinoma |
| Note | Co2-free culture |
| Unit | Piece |
| Specification | 1EA |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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