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A plant immune protein enables broad antitumor response by rescuing microRNA deficiency

Mouse totipotent stem cells captured and maintained through spliceosomal repression

Reduction of choroidal neovascularization via cleavable VEGF antibodies conjugated to exosomes derived from regulatory T cells

Triggering Reactive Oxygen Species Field Effect Transistor Based on HIF-1α Signaling for Enhanced Chemodynamic Therapy

Extracellular Vesicle ITGAM and ITGB2 Mediate Severe Acute Pancreatitis-Related Acute Lung Injury

ERK and USP5 govern PD-1 homeostasis via deubiquitination to modulate tumor immunotherapy

Nutrient Element Decorated Polyetheretherketone Implants Steer Mitochondrial Dynamics for Boosted Diabetic Osseointegration

Extracellular Matrix/Glycopeptide Hybrid Hydrogel as an Immunomodulatory Niche for Endogenous Cardiac Repair after Myocardial Infarction

MDM2 upregulation induces mitophagy deficiency via Mic60 ubiquitination in fetal microglial inflammation and consequently neuronal DNA damage caused by exposure to ZnO-NPs during pregnancy

Macrophage Polarization Modulated by NF-κB in Polylactide Membranes-Treated Peritendinous Adhesion

Cross-reactive antibodies against dust mite-derived enolase induce neutrophilic airway inflammation

Kidney targeting peptide-modified biomimetic nanoplatforms for treatment of acute kidney injury

An aminocaproic acid-grafted chitosan derivative with superior antibacterial and hemostatic properties for the prevention of secondary bleeding

miR-124-3p delivered by exosomes from heme oxygenase-1 modified bone marrow mesenchymal stem cells inhibits ferroptosis to attenuate ischemia-reperfusion injury in steatotic grafts

SO2 prodrug doped nanorattles with extra-high drug payload for “collusion inside and outside” photothermal/pH triggered - gas therapy

Cold exposure protects against medial arterial calcification development via autophagy

Loss of 4.1N in Epithelial Ovarian Cancer Results in EMT and Matrix-detached Cell Death Resistance

Hierarchically Porous Implants Orchestrating a Physiological Viscoelastic and Piezoelectric Microenvironment for Bone Regeneration

NIR-Responsive Spatiotemporally Controlled Cyanobacteria Micro-Nanodevice for Intensity-Modulated Chemotherapeutics in Rheumatoid Arthritis

Amide-containing neoepitopes: the key factor in the preparation of hapten-specific antibodies and a strategy to overcome

Self-targeting visualizable hyaluronate nanogel for synchronized intracellular release of doxorubicin and cisplatin in combating multidrug-resistant breast cancer

Comparative Proteomic Analysis of Polarized Human THP-1 and Mouse RAW264.7 Macrophages

Hyaluronic acid oligosaccharides modified mineralized collagen and chitosan with enhanced osteoinductive properties for bone tissue engineering

Hyaluronic acid oligosaccharide-collagen mineralized product and aligned nanofibers with enhanced vascularization properties in bone tissue engineering

NIR-triggered engineered photosynthetic micro? nanodevice for reversing the hypoxic tumor immunosuppressive microenvironment

MiR-106b and miR-93 regulate cell progression by suppression of PTEN via PI3K/Akt pathway in breast cancer

The RBP1?CKAP4 axis activates oncogenic autophagy and promotes cancer progression in oral squamous cell carcinoma

Mesenchymal Stem Cells-Derived Exosomes as Dexamethasone Delivery Vehicles for Autoimmune Hepatitis Therapy

Assessing the combinatorial cytotoxicity of the exogenous contamination with BDE-209, bisphenol A, and acrylamide via high-content analysis

A novel rapid modularized hepatitis B core virus like particle based platform for personalized cancer vaccine preparation via fixed point coupling

Fabrication of multi-functional carbon dots based on “one stone, three birds” strategy and its applications for dual mode Fe3+ detection, effective promotion on cell proliferation and treatment on ferric toxicosis in vitro

Natural polymer based bioadhesive with self-healing behavior and improved antibacterial properties

Hyaluronic acid bioinspired polymers for the regulation of cell chondrogenic and osteogenic differentiation

Sulfonated glycosaminoglycan bioinspired carbon dots for effective cellular labelling and promotion of the differentiation of mesenchymal stem cells

Deletion of the H240R Gene of African Swine Fever Virus Decreases Infectious Progeny Virus Production due to Aberrant Virion Morphogenesis and Enhances the Inflammatory Cytokines Expression in Porcine Macrophages

Inhibition effects of 7-phloro-eckol from Ecklonia cava on metastasis and angiogenesis induced by hypoxia through regulation of AKT/mTOR and ERK signaling pathways

The effects of fluoride on neuronal function occurs via cytoskeleton damage and decreased signal transmission

AhR-mediated CYP1A1 and ROS overexpression are involved in hepatotoxicity of decabromodiphenyl ether (BDE-209)

Protective effect of Amomum Roxb. essential oils in lipopolysaccharide-induced acute lung injury mice and its metabolomics

A Peptide-Based Small RNA Delivery System to Suppress Tumor Growth by Remodeling the Tumor Microenvironment

Acidic pH environment induces autophagy in osteoblasts

Reparative Effects of Ethanol-Induced Intestinal Barrier Injury by Flavonoid Luteolin via MAPK/NF-κB/MLCK and Nrf2 Signaling Pathways

Polybrominated diphenyl ethers quinone exhibits neurotoxicity by inducing DNA damage, cell cycle arrest, apoptosis and p53-driven adaptive response in microglia BV2 cells

A Host Factor GPNMB Restricts Porcine Circovirus Type 2 (PCV2) Replication and Interacts With PCV2 ORF5 Protein

Fabrication of fluorescent hybrid nanomaterials based on carbon dots and its applications for improving the selective detection of Fe (III) in different matrices and cellular imaging

Macropinocytosis-dependent endocytosis of Japanese flounder IgM+ B cells and its regulation by CD22

Neuronostatin promotes soluble A??1-42 oligomers ?Cinduced spatial learning and memory impairments in mice

Diterpene pekinenal from euphorbia pekinensis radix induced IEC-6 cells apoptosis mediated by mitochondria and death receptors

LncRNA SNHG1 promotes ??-synuclein aggregation and toxicity by targeting miR-15b-5p to activate SIAH1 in human neuroblastoma SH-SY5Y cells

Rapamycin ameliorates corneal injury after alkali burn through methylation modification in mouse TSC1 and mTOR genes

Effect of acute exposure to PFOA on mouse liver cells in vivo and in vitro

ARHGAP6 regulates the proliferation, migration and invasion of lung cancer cells

PYGB siRNA inhibits the cell proliferation of human osteosarcoma cell lines

Expression of USP22 and the chromosomal passenger complex is an indicator of malignant progression in oral squamous cell carcinoma

Centromere protein U promotes cell proliferation, migration and invasion involving Wnt/??-catenin signaling pathway in non-small cell lung cancer

miR?\21 represses FasL in microglia and protects against microglia?\mediated neuronal cell death following hypoxia/ischemia