{{cart_num}}
My CartCAS：39831-55-5
Molecular Formula：C22H43N5O13·2H2SO4
Molecular Weight：781.76
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Appearance：White to off-white Solid
Qty：
Size：
| CAS | 39831-55-5 |
| Name | Amikacin Sulfate |
| Molecular Formula | C22H43N5O13·2H2SO4 |
| Molecular Weight | 781.76 |
| Solubility | Soluble in Water ≥10mg/mL |
| Enzyme Activity/Titer | 674-786μg/mg |
| Appearance | White to off-white Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| EC | EINECS 254-648-6 |
| MDL | MFCD00167475 |
| SMILES | OS(O)(=O)=O.OS(O)(=O)=O.O[C@@H]1[C@H]([C@@H](C[C@H](N)[C@H]1O[C@@]([C@@H]([C@@H](O)[C@@H]2O)O)([H])O[C@@H]2CN)NC([C@@H](O)CCN)=O)O[C@@]([C@@H]([C@@H](N)[C@@H]3O)O)([H])O[C@@H]3CO |
| InChIKey | FXKSEJFHKVNEFI-GCZBSULCSA-N |
| InChI | InChI=1S/C22H43N5O13.2H2O4S/c23-2-1-8(29)20(36)27-7-3-6(25)18(39-22-16(34)15(33)13(31)9(4-24)37-22)17(35)19(7)40-21-14(32)11(26)12(30)10(5-28)38-21;2*1-5(2,3)4/h6-19,21-22,28-35H,1-5,23-26H2,(H,27,36);2*(H2,1,2,3,4)/t6-,7+,8-,9+,10+,11-,12+,13+,14+,15-,16+,17-,18+,19-,21+,22+;;/m0../s1 |
| PubChem CID | 38351 |
| Target Point | Bacterial |
| Passage | Anti-infection |
| Background | It is an aminoglycoside antibiotic. It has bactericidal effect, acts on the 30S subunit of bacterial ribosome, inhibits bacterial protein synthesis, and has a good effect on most Enterobacteriaceae bacteria. |
| Biological Activity | Amikacin disulfate (BAY 41-6551 dissulfate) is an aminoglycoside antibiotic and a semisynthetic analog of kanamycin. Amikacin disulfate is bactericidal, acting directly on the 30S and 50S bacerial ribosomal subunits to inhibit protein synthesis. Amikacin disulfate is very active against most Gram-negative bacteria including gentamicin- and tobramycin-resistant strains. Amikacin disulfate also inhibits the infections caused by susceptible Nocardia and nontuberculous mycobacteria[1-2]. |
| Data Literature Source | [1]. Edson，R.S. and C.L. Terrell，The aminoglycosides. Mayo Clin Proc，1999. 74(5): p. 519-28. [2]. Ristuccia AM，et al. An overview of amikacin. Ther Drug Monit. 1985;7(1):12-25. [3]. Sian R Kitcher，et al. ORC-13661 Protects Sensory Hair Cells From Aminoglycoside and Cisplatin Ototoxicity. JCI Insight. 2019 Aug 8;4(15):e126764. |
| Unit | Bottle |
| Specification | 100mg 10mM*1mL in Water 500mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
Sorry, there is no more information.
Sorry, there is no more information.
Co-Occurrence of the blaKPC-2 and Mcr-3.3 Gene in Aeromonas caviae SCAc2001 Isolated from Patients with Diarrheal Disease
Click to check >>Author：Tang L; Huang J; She J; Zhao K; Zhou Y
IF：3.9000
Publish_to：Infect Drug Resist
PMID：32547122
Manual Download
