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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Cell Cycle > BergaptenCAS：484-20-8
Molecular Formula：C12H8O4
Molecular Weight：216.19
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：HPLC≥98%
Appearance：White to off-white Solid
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| CAS | 484-20-8 |
| Name | Bergapten |
| Molecular Formula | C12H8O4 |
| Molecular Weight | 216.19 |
| Solubility | Soluble in DMSO |
| Purity | HPLC≥98% |
| Appearance | White to off-white Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| EC | EINECS 207-604-5 |
| MDL | MFCD00010272 |
| SMILES | O=C1C=CC2=C(OC)C3=C(OC=C3)C=C2O1 |
| InChIKey | BGEBZHIAGXMEMV-UHFFFAOYSA-N |
| InChI | InChI=1S/C12H8O4/c1-14-12-7-2-3-11(13)16-10(7)6-9-8(12)4-5-15-9/h2-6H,1H3 |
| PubChem CID | 2355 |
| Target Point | Others |
| Passage | Others |
| Background | Bergapten is a psoralen with anti-inflammatory and antitumor activities. |
| Biological Activity | Bergapten， as a natural anti-inflammatory and anti-tumor agent isolated from bergamot essential oil， other citrus essential oils， and grapefruit juice， has been proven to have the ability to attenuate a number of metabolic disorders.[2] |
| Data Literature Source | [1]. Lee YM，et al. Effects of 5-methoxypsoralen (5-MOP) on arylamine N-acetyltransferase activity in the stomach and colon of rats and human stomach and colon tumor cell lines. In Vivo. 2005 Nov-Dec;19(6):1061-9. [2]. Li XJ，et al. Bergapten exerts inhibitory effects on diabetes-related osteoporosis via the regulation of the PI3K/AKT，JNK/MAPK and NF-κB signaling pathways in osteoprotegerin knockout mice. Int J Mol Med. 2016 Dec;38(6):1661-1672. |
| Unit | Bottle |
| Specification | 50mg 10mM*1mL in DMSO 100mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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Bergapten alleviates osteoarthritis by regulating the ANP32A/ATM signaling pathway
Click to check >>Author：He Y; Zisan Z; Lu Z; Zheng L; Zhao J
IF：2.2110
Publish_to：FEBS Open Bio
PMID：31037830
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