Cisplatin
Cat.No:IC0440 Solarbio
CAS:15663-27-1
Molecular Formula:Cl2H6N2Pt
Molecular Weight:300.05
Storage:Powder:2-8℃,2 years
Purity:HPLC≥98%
Appearance:Light yellow to yellow Solid
Qty:
Size:
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CisplatinCAS:15663-27-1
Molecular Formula:Cl2H6N2Pt
Molecular Weight:300.05
Storage:Powder:2-8℃,2 years
Purity:HPLC≥98%
Appearance:Light yellow to yellow Solid
Qty:
Size:
CAS | 15663-27-1 |
Name | Cisplatin |
Molecular Formula | Cl2H6N2Pt |
Molecular Weight | 300.05 |
Solubility | Soluble in DMF(This product is not stable in solution, it is recommended that you use it now) |
Purity | HPLC≥98% |
Appearance | Light yellow to yellow Solid |
Storage | Powder:2-8℃,2 years |
EC | EINECS 239-733-8 |
MDL | MFCD00011623 |
SMILES | [Cl-][Pt+2]([Cl-])([NH3])[NH3] |
InChIKey | DQLATGHUWYMOKM-UHFFFAOYSA-L |
InChI | InChI=1S/2ClH.2H2N.Pt/h2*1H;2*1H2;/q;;2*-1;+4/p-2 |
PubChem CID | 2767 |
Target Point | Ferroptosis;DNA Crosslinker |
Passage | Apoptosis |
Background | Cisplatin cross-linking with DNA can cause DNA damage in cancer cells and can be used in the research of anti-tumor chemotherapy drugs. Cisplatin can activate ferroptosis and induce autophagy. |
Biological Activity | Cisplatin 是一种抗肿瘤化疗药物,它与 DNA 交联引起癌细胞中DNA损伤[1-4]。 |
Data Literature Source | [1]. Wang X,et al. Requirement for ERK activation in cisplatin-induced apoptosis. J Biol Chem. 2000 Dec 15;275(50):39435-43. [2]. Cummings BS,et al. Cisplatin-induced renal cell apoptosis: caspase 3-dependent and -independent pathways. J Pharmacol Exp Ther. 2002 Jul;302(1):8-17. [3]. Park HR,et al. Enhanced antitumor efficacy of cisplatin in combination with HemoHIM in tumor-bearing mice. BMC Cancer. 2009 Mar 17;9:85. [4]. Shimeda Y,et al. Protective effects of capsaicin against cisplatin-induced nephrotoxicity in rats. Biol Pharm Bull. 2005 Sep;28(9):1635-8. |
Unit | Bottle |
Specification | 20mg 100mg 200mg 500mg |
Remark:These protocols are for reference only. Solarbio does not independently validate these methods.
Note:
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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您好,我想请问下,从这购买的顺铂,想用高效液相色谱检测一下,请问它的检测条件是什么呢?您们的说明书没有说明诶 2022-07-05 10:13:13
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