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Danshensu

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Cat.No：ID0050 Solarbio

CAS：76822-21-4

Molecular Formula：C₉H₁₀O₅

Molecular Weight：198.17

Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year

Purity：HPLC≥98%

Appearance：White to off-white Solid

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Product Information

CAS	76822-21-4
Name	Danshensu
Molecular Formula	C₉H₁₀O₅
Molecular Weight	198.17
Solubility	Soluble in Water ≥2mg/mL;Soluble in Ethanol/DMSO ≥10mg/mL
Purity	HPLC≥98%
Appearance	White to off-white Solid
Storage	Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
MDL	MFCD09038703
SMILES	OC1=C(O)C=CC(C[C@@H](O)C(O)=O)=C1
InChIKey	PAFLSMZLRSPALU-MRVPVSSYSA-N
InChI	InChI=1S/C9H10O5/c10-6-2-1-5(3-7(6)11)4-8(12)9(13)14/h1-3,8,10-12H,4H2,(H,13,14)/t8-/m1/s1
PubChem CID	11600642
Target Point	Nrf2;Cytochrome P450
Passage	NF-κB;Metabolic Enzyme&Protease
Background	Danshensu is an orally active phenolic compound that activates the Nrf2 signaling pathway and has protective cardiovascular activity.
Biological Activity	Danshensu 是丹参的有效成分，能够激活 Nrf2 信号通路，保护心血管。Danshensu 可抑制 CYP2E1 和 CYP2C9，对应的IC50值分别为36.63 μm和 75.76 μm。[1-3]
Data Literature Source	[1]. YG Cao，et al. Beneficial effects of danshensu，an active component of Salvia miltiorrhiza，on homocysteine metabolism via the trans-sulphuration pathway in rats. Br J Pharmacol. 2009 Jun; 157(3): 482–490. [2]. Yu J，et al. Danshensu protects isolated heart against ischemia reperfusion injury through activation of Akt/ERK1/2/Nrf2 signaling. Int J Clin Exp Med. 2015 Sep 15;8(9):14793-804.
Unit	Bottle
Specification	10mg 10mM*1mL in Water 50mg

Remark：These protocols are for reference only. Solarbio does not independently validate these methods.

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