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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > PI3K/Akt/mTOR > DanthronCAS：117-10-2
Molecular Formula：C14H8O4
Molecular Weight：240.21
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：HPLC≥97%
Appearance：Yellow to orange Solid
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| CAS | 117-10-2 |
| Name | Danthron |
| Molecular Formula | C14H8O4 |
| Molecular Weight | 240.21 |
| Solubility | Soluble in DMSO ≥10mg/mL |
| Purity | HPLC≥97% |
| Appearance | Yellow to orange Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| EC | EINECS 204-173-5 |
| MDL | MFCD00001211 |
| SMILES | O=C1C2=C(C=CC=C2O)C(C3=CC=CC(O)=C13)=O |
| InChIKey | QBPFLULOKWLNNW-UHFFFAOYSA-N |
| InChI | InChI=1S/C14H8O4/c15-9-5-1-3-7-11(9)14(18)12-8(13(7)17)4-2-6-10(12)16/h1-6,15-16H |
| PubChem CID | 2950 |
| Target Point | AMPK |
| Passage | PI3K/Akt/mTOR;Epigenetics |
| Background | Danthron regulates glucose and lipid metabolism by activating AMPK. |
| Biological Activity | Danthron 通过激活 AMPK 来调节葡萄糖和脂质代谢[1-2]。 |
| Data Literature Source | [1]. Zhou R，et al. Danthron activates AMP-activated protein kinase and regulates lipid and glucose metabolism in vitro. Acta Pharmacol Sin. 2013 Aug;34(8):1061-9. [2]. Zhang H，et al. Danthron functions as a retinoic X receptor antagonist by stabilizing tetramers of the receptor. J Biol Chem. 2011 Jan 21;286(3):1868-75 |
| Unit | Bottle |
| Specification | 10mM*1mL in DMSO 50mg 100mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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