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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Immunology & Inflammation > (-)-Epicatechin gallateCAS：1257-08-5
Molecular Formula：C22H18O10
Molecular Weight：442.37
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：HPLC≥98%
Appearance：White to off-white Solid
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| CAS | 1257-08-5 |
| Name | (-)-Epicatechin gallate |
| Molecular Formula | C22H18O10 |
| Molecular Weight | 442.37 |
| Solubility | Soluble in DMSO ≥25mg/mL |
| Purity | HPLC≥98% |
| Appearance | White to off-white Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| EC | EINECS 603-088-4 |
| MDL | MFCD00075936 |
| SMILES | O=C(O[C@H]1[C@@H](C2=CC=C(O)C(O)=C2)OC3=CC(O)=CC(O)=C3C1)C4=CC(O)=C(O)C(O)=C4 |
| InChIKey | LSHVYAFMTMFKBA-TZIWHRDSSA-N |
| InChI | InChI=1S/C22H18O10/c23-11-6-14(25)12-8-19(32-22(30)10-4-16(27)20(29)17(28)5-10)21(31-18(12)7-11)9-1-2-13(24)15(26)3-9/h1-7,19,21,23-29H,8H2/t19-,21-/m1/s1 |
| PubChem CID | 107905 |
| Target Point | COX |
| Passage | Immunology & Inflammation |
| Background | (-)-Epicatechin gallate inhibits cyclooxygenase-1 (COX-1). |
| Biological Activity | Epicatechin gallate 抑制环加氧酶-1 (COX-1) , IC50 为 7.5 μM。[1] |
| Data Literature Source | [1]. Waffo-Téguo P，et al. Potential cancer-chemopreventive activities of wine stilbenoids and flavans extracted from grape (Vitis vinifera) cell cultures. Nutr Cancer. 2001;40(2):173-9. [2]. Takizawa Y，et al. Pharmacokinetics of (-)-epicatechin-3-O-gallate，an active component of Onpi-to，in rats. Biol Pharm Bull. 2003 May;26(5):608-12. |
| Unit | Bottle |
| Specification | 5mg 10mM*1mL in DMSO 10mg 50mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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