{{cart_num}}
My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Others > GenipinCAS：6902-77-8
Molecular Formula：C11H14O5
Molecular Weight：226.23
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：HPLC≥98%
Appearance：White to off-white Solid
Qty：
Size：
| CAS | 6902-77-8 |
| Name | Genipin |
| Molecular Formula | C11H14O5 |
| Molecular Weight | 226.23 |
| Solubility | Soluble in DMSO ≥25mg/mL |
| Purity | HPLC≥98% |
| Appearance | White to off-white Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| EC | EINECS 300-006-4 |
| MDL | MFCD00888600 |
| SMILES | O=C(C1=CO[C@@H](O)[C@@]2([H])[C@]1([H])CC=C2CO)OC |
| InChIKey | AZKVWQKMDGGDSV-BCMRRPTOSA-N |
| InChI | InChI=1S/C11H14O5/c1-15-10(13)8-5-16-11(14)9-6(4-12)2-3-7(8)9/h2,5,7,9,11-12,14H,3-4H2,1H3/t7-,9-,11-/m1/s1 |
| PubChem CID | 442424 |
| Target Point | Others |
| Passage | Others |
| Background | Genipin is an active glycoside derived from Geniposide of iridoid glycosides， which has a variety of biological activities， such as protein regulation， anti-tumor， anti-inflammation， immunosuppressive， anti-thrombotic and protection of hippocampal neurons. Genipin inhibits UCP2 (uncoupling protein 2) in cells. Genipin can also be used in type 2 diabetes research. |
| Data Literature Source | [1]. Ma C，et al. Genipin stimulates glucose transport in C2C12 myotubes via IRS-1 and calcium- dependent mechanism. J Endocrinol. 2012 Dec 20. [2]. Parton LE，et al. Glucose sensing by POMC neurons regulates glucose homeostasis and is impaired in obesity. Nature. 2007 Sep 13;449(7159):228-32. [3]. Kim BC，et al. Genipin-induced apoptosis in hepatoma cells is mediated by reactive oxygen species/c-Jun NH2-terminal kinase-dependent activation of mitochondrial pathway. Biochem Pharmacol. 2005 Nov 1;70(9):1398-407. [4]. Ye D，et al. Genipin normalizes depression-like behavior induced by prenatal stress through inhibiting DNMT1. Epigenetics. 2018 Mar 9:1-22 |
| Unit | Bottle |
| Specification | 10mg 10mM*1mL in DMSO 20mg 100mg 500mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
Sorry, there is no more information.
Sorry, there is no more information.
Irisin Contributes to Neuroprotection by Promoting Mitochondrial Biogenesis After Experimental Subarachnoid Hemorrhage
Click to check >>Author：Tu T; Yin S; Pang J; Zhang X; Zhang L; Zhang Y; Xi
IF：4.8000
Publish_to：Front Aging Neurosci
PMID：33613273
Manual Download
