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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Others > 5'-GTP Trisodium SaltCAS：36051-31-7
Molecular Formula：C10H13N5O14P3Na3
Molecular Weight：589.13
Storage：Powder:-20℃，1 year;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：HPLC≥95%
Appearance：White to off-white Solid
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| CAS | 36051-31-7 |
| Name | 5'-GTP Trisodium Salt |
| Molecular Formula | C10H13N5O14P3Na3 |
| Molecular Weight | 589.13 |
| Solubility | Soluble in Water ≥10mg/mL |
| Purity | HPLC≥95% |
| Appearance | White to off-white Solid |
| Storage | Powder:-20℃，1 year;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| EC | EINECS 252-847-2 |
| MDL | MFCD03787968 |
| SMILES | O[C@@H]([C@H]([C@H](N1C=NC2=C1NC(N)=NC2=O)O3)O)[C@H]3COP(O)(OP(OP(O[Na])(O[Na])=O)(O[Na])=O)=O |
| InChIKey | KZRMTEVIDYXWQW-CYCLDIHTSA-K |
| InChI | InChI=1S/C10H16N5O14P3.3Na/c11-10-13-7-4(8(18)14-10)12-2-15(7)9-6(17)5(16)3(27-9)1-26-31(22,23)29-32(24,25)28-30(19,20)21;;;/h2-3,5-6,9,16-17H,1H2,(H,22,23)(H,24,25)(H2,19,20,21)(H3,11,13,14,18);;;/q;3*+1/p-3/t3-,5-,6-,9-;;;/m1.../s1 |
| PubChem CID | 135445727 |
| Target Point | Others |
| Passage | Others |
| Background | 5'-GTP Trisodium Salt is a G protein signal transduction activator， which can induce the release of exosomes containing guanoside molecules by upregulating the expression of miRNA (miR133a， miR133b) and myogenic regulatory factors. To promote myogenic cell differentiation， it has the potential to be used in biosynthesis and skeletal muscle regeneration. |
| Biological Activity | The extracellular guanosine 5'-triphosphate， GTP， has been demonstrated to be an enhancer of myogenic cell differentiation in a murine cell line.[1] |
| Data Literature Source | [1]. Pietrangelo T，Di Filippo ES，Locatelli M，Piacenza F，Farina M，Pavoni E，Di Donato A，Innosa D，Provinciali M，Fulle S. Extracellular Guanosine 5'-Triphosphate Induces Human Muscle Satellite Cells to Release Exosomes Stuffed With Guanosine. Front Pharmacol. 2018 Mar 16;9:152. |
| Unit | Bottle |
| Specification | 5mg 10mM*1mL in Water 10mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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Artificially designed routes for the conversion of starch to value-added mannosyl compounds through coupling in vitro and in vivo metabolic engineering strategies
Click to check >>Author：Tian C; Yang J; Li Y; Zhang T; Li J; Ren C; Men Y;
IF：8.4000
Publish_to：Metab Eng
PMID：32623008
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