Milrinone
Cat.No:IM0260 Solarbio
CAS:78415-72-2
Molecular Formula:C12H9N3O
Molecular Weight:211.22
Storage:Powder:-20℃,2 years;Insolvent(Mother Liquid):-20℃,6 months;-80℃,1 year
Purity:HPLC≥98%
Appearance:White to off-white Solid
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MilrinoneCAS:78415-72-2
Molecular Formula:C12H9N3O
Molecular Weight:211.22
Storage:Powder:-20℃,2 years;Insolvent(Mother Liquid):-20℃,6 months;-80℃,1 year
Purity:HPLC≥98%
Appearance:White to off-white Solid
Qty:
Size:
CAS | 78415-72-2 |
Name | Milrinone |
Molecular Formula | C12H9N3O |
Molecular Weight | 211.22 |
Solubility | Soluble in DMSO |
Purity | HPLC≥98% |
Appearance | White to off-white Solid |
Storage | Powder:-20℃,2 years;Insolvent(Mother Liquid):-20℃,6 months;-80℃,1 year |
EC | EINECS 278-903-6 |
MDL | MFCD00133539 |
SMILES | CC(N1)=C(C2=CC=NC=C2)C=C(C#N)C1=O |
InChIKey | PZRHRDRVRGEVNW-UHFFFAOYSA-N |
InChI | InChI=1S/C12H9N3O/c1-8-11(9-2-4-14-5-3-9)6-10(7-13)12(16)15-8/h2-6H,1H3,(H,15,16) |
PubChem CID | 4197 |
Target Point | Phosphodiesterase (PDE) |
Passage | Metabolic Enzyme&Protease |
Background | Milrinone is a PDE3 inhibitor. |
Biological Activity | Milrinone 是 PDE3 抑制剂,也是一种强心药、血管舒张药。[1-4] |
Data Literature Source | [1]. Santhosh KT,et al. Milrinone attenuates thromboxane receptor-mediated hyperresponsiveness in hypoxic pulmonary arterial myocytes. Br J Pharmacol. 2011 Jul;163(6):1223-36. [2]. Hentschel T,et al. Inhalation of the phosphodiesterase-3 inhibitor milrinone attenuates pulmonary hypertension in a rat model of congestive heart failure. Anesthesiology. 2007 Jan;106(1):124-31. [3]. Kishi T,et al. Effects of milrinone on left ventricular end-systolic pressure-volume relationship of rat hearts in situ. Clin Exp Pharmacol Physiol. 2001 Sep;28(9):737-42. [4]. Taylor MS,et al. Effect of milrinone on small mesenteric artery vasoconstriction: role of K(+) channels. Am J Physiol. 1999 Jul;277(1 Pt 1):G69-78 |
Unit | Bottle |
Specification | 10mg 10mM*1mL in DMSO 50mg |
Remark:These protocols are for reference only. Solarbio does not independently validate these methods.
Note:
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
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3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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