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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Immunology & Inflammation > Palmatine ChlorideCAS：10605-02-4
Molecular Formula：C21H22ClNO4
Molecular Weight：387.86
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：HPLC≥98%
Appearance：Light yellow to yellow Solid
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| CAS | 10605-02-4 |
| Name | Palmatine Chloride |
| Molecular Formula | C21H22ClNO4 |
| Molecular Weight | 387.86 |
| Solubility | Soluble in Water/DMSO ≥5mg/mL |
| Purity | HPLC≥98% |
| Appearance | Light yellow to yellow Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| MDL | MFCD00016656 |
| SMILES | COC1=C(OC)C2=C[N+]3=C(C4=CC(OC)=C(OC)C=C4CC3)C=C2C=C1.[Cl-] |
| InChIKey | RLQYRXCUPVKSAW-UHFFFAOYSA-M |
| InChI | InChI=1S/C21H22NO4.ClH/c1-23-18-6-5-13-9-17-15-11-20(25-3)19(24-2)10-14(15)7-8-22(17)12-16(13)21(18)26-4;/h5-6,9-12H,7-8H2,1-4H3;1H/q+1;/p-1 |
| PubChem CID | 73442 |
| Target Point | Indoleamine 2,3-Dioxygenase (IDO) |
| Passage | Immunology & Inflammation;Metabolic Enzyme&Protease |
| Background | Palmatine chloride is an orally active and irreversible indoleamine 2，3-dioxygenase 1 (IDO-1) inhibitor with IC50s of 3 μM and 157μM against HEK 293-hIDO-1 and rhIDO-1， respectively. Palmatine chloride can also inhibit West Nile virus (WNV) NS2B-NS3 protease in an uncompetitive manner with an IC50 of 96 μM. Palmatine chloride shows anti-cancer， anti-oxidation， anti-inflammatory， neuroprotection， antibacterial， anti-viral activities[1-5]. |
| Unit | Bottle |
| Specification | 10mg 10mM*1mL in DMSO 50mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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