{{cart_num}}
My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Protein Tyrosine Kinase/PTK > PiceatannolCAS：10083-24-6
Molecular Formula：C14H12O4
Molecular Weight：244.24
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：HPLC≥98%
Appearance：White to brown Solid
Qty：
Size：
| CAS | 10083-24-6 |
| Name | Piceatannol |
| Molecular Formula | C14H12O4 |
| Molecular Weight | 244.24 |
| Solubility | Soluble in DMSO |
| Purity | HPLC≥98% |
| Appearance | White to brown Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| EC | EINECS 600-132-4 |
| MDL | MFCD00221715 |
| SMILES | OC1=CC=C(/C=C/C2=CC(O)=CC(O)=C2)C=C1O |
| InChIKey | CDRPUGZCRXZLFL-OWOJBTEDSA-N |
| InChI | InChI=1S/C14H12O4/c15-11-5-10(6-12(16)8-11)2-1-9-3-4-13(17)14(18)7-9/h1-8,15-18H/b2-1+ |
| PubChem CID | 667639 |
| Target Point | Syk |
| Passage | Protein Tyrosine Kinase/RTK |
| Background | Piceatannol is a Syk inhibitor that reduces iNOS expression induced by TNF and can be used in studies of acute lung injury (ALI). Piceatannol is a polyphenol stilbene that has anti-cancer and anti-inflammatory activities. |
| Biological Activity | Piceatannol，是一种天然二苯乙烯，是选择性Syk抑制剂，比作用于Lyn选择性高10倍左右。Piceatannol也可以有效地抑制 PKA, PKC, MLCK,和 CDPK， IC50 分别为 3 μM, 8 μM, 12 μM, 以及19 μM [1-2] |
| Data Literature Source | [1] Oliver JM，et al. J Biol Chem，1994，269(47)，29697-29703. [2] Wang BH，et al. Planta Med，1998，64(3)，195-199. [3] Su L，et al. J Biol Chem，2000，275(17)，12661-12666. [4] Ashikawa K，et al. J Immunol，2002，169(11)，6490-6497. [5] Kim YH，et al. Int Immunopharmacol，2008，8(12)，1695-1702. [6] Minakawa M，et al. Biochem Biophys Res Commun，2012，422(3)，469-475. |
| Unit | Bottle |
| Specification | 10mg 10mM*1mL in DMSO 20mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
Sorry, there is no more information.
Sorry, there is no more information.
Sorry, there is no more information.
Manual Download
