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Prim-O-glucosylcimifugin

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Cat.No：IP0370 Solarbio

CAS：80681-45-4

Molecular Formula：C₂₂H₂₈O₁₁

Molecular Weight：468.45

Storage：Powder:-20℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year

Purity：HPLC≥98%

Appearance：White to off-white Solid

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Product Information

CAS	80681-45-4
Name	Prim-O-glucosylcimifugin
Molecular Formula	C₂₂H₂₈O₁₁
Molecular Weight	468.45
Solubility	Soluble in Water ≥20mg/mL;Soluble in DMSO ≥5mg/mL
Purity	HPLC≥98%
Appearance	White to off-white Solid
Storage	Powder:-20℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
MDL	MFCD09037394
SMILES	COC1=C(C[C@@H](C(C)(O)C)O2)C2=CC(OC(CO[C@@H]([C@@H]([C@@H](O)[C@@H]3O)O)O[C@@H]3CO)=C4)=C1C4=O
InChIKey	XIUVHOSBSDYXRG-UVTAEQIVSA-N
InChI	InChI=1S/C22H28O11/c1-22(2,28)15-5-10-12(32-15)6-13-16(20(10)29-3)11(24)4-9(31-13)8-30-21-19(27)18(26)17(25)14(7-23)33-21/h4,6,14-15,17-19,21,23,25-28H,5,7-8H2,1-3H3/t14-,15+,17-,18+,19-,21-/m1/s1
PubChem CID	14034912
Target Point	NO Synthase
Passage	Immunology & Inflammation
Background	Prim-O-glucosylcimifugin has potent anti-inflammatory activity. Inhibits iNOS and COX-2 expression by modulating JAK2/STAT3 signaling.
Biological Activity	Prim-O-glucosylcimifugin 具有强效的抗炎作用。通过调节 JAK2/STAT3 信号传导可抑制 iNOS 和 COX-2 表达。[1-2]
Data Literature Source	[1]. Zhou J，et al. Prim-O-glucosylcimifugin Attenuates Lipopolysaccharideinduced Inflammatory Response in RAW 264.7 Macrophages. Pharmacogn Mag. 2017 Jul-Sep;13(51):378-384. [2]. Chen N，et al. Prime-O-glucosylcimifugin attenuates lipopolysaccharide-induced acute lung injury in mice. Int Immunopharmacol. 2013 Jun;16(2):139-47.
Unit	Bottle
Specification	5mg 10mM*1mL in DMSO

Remark：These protocols are for reference only. Solarbio does not independently validate these methods.

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