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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Immunology & Inflammation > Salicylic acidCAS：69-72-7
Molecular Formula：C7H6O3
Molecular Weight：138.12
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：HPLC≥98%
Appearance：White to off-white Solid
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| CAS | 69-72-7 |
| Name | Salicylic acid |
| Molecular Formula | C7H6O3 |
| Molecular Weight | 138.12 |
| Solubility | Soluble in DMSO |
| Purity | HPLC≥98% |
| Appearance | White to off-white Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| EC | EINECS 200-712-3 |
| MDL | MFCD00002439 |
| SMILES | O=C(O)C1=CC=CC=C1O |
| InChIKey | YGSDEFSMJLZEOE-UHFFFAOYSA-N |
| InChI | InChI=1S/C7H6O3/c8-6-4-2-1-3-5(6)7(9)10/h1-4,8H,(H,9,10) |
| PubChem CID | 338 |
| Target Point | COX |
| Passage | Immunology & Inflammation |
| Background | Salicylic acid, a fat-Soluble organic acid, is an inhibitor of ethylene biosynthesis and cyclooxygenase activity. |
| Biological Activity | Salicylic acid 抑制 COX-2 活性，抑制作用与转录因子 (NF-κB) 激活无关。[1-2] |
| Data Literature Source | [1]. Mitchell JA，et al. Sodium salicylate inhibits cyclo-oxygenase-2 activity independently of transcription factor (nuclear factor kappaB) activation: role of arachidonic acid. Mol Pharmacol. 1997 Jun;51(6):907-12. [2]. Nixon M，et al. Salicylate downregulates 11β-HSD1 expression in adipose tissue in obese mice and in humans，mediating insulin sensitization. Diabetes. 2012 Apr;61(4):790-6 |
| Unit | Bottle |
| Specification | 50mg 10mM*1mL in DMSO |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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Zhao Y, et al. Food Chem. 2021 Oct 1;358:129867.
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