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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Apoptosis > SanguinarineCAS：2447-54-3
Molecular Formula：C20H14NO4
Molecular Weight：332.33
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：HPLC≥98%
Appearance：Solid
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| CAS | 2447-54-3 |
| Name | Sanguinarine |
| Molecular Formula | C20H14NO4 |
| Molecular Weight | 332.33 |
| Solubility | Soluble in DMSO |
| Purity | HPLC≥98% |
| Appearance | Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| EC | EINECS 219-503-3 |
| MDL | MFCD00064925 |
| SMILES | C[N+]1=CC2=C3C(OCO3)=CC=C2C(C=CC4=C5)=C1C4=CC6=C5OCO6 |
| InChIKey | INVGWHRKADIJHF-UHFFFAOYSA-N |
| InChI | InChI=1S/C20H14NO4/c1-21-8-15-12(4-5-16-20(15)25-10-22-16)13-3-2-11-6-17-18(24-9-23-17)7-14(11)19(13)21/h2-8H,9-10H2,1H3/q+1 |
| PubChem CID | 5154 |
| Target Point | Others |
| Passage | Others |
| Background | Sanguinarine is an alkaloid that can stimulate cell apoptosis by activating the production of reactive oxygen species (ROS). Sanguinarine induced apoptosis and JNK and NF- κ B activation. |
| Biological Activity | Sanguinarine 是一种来源于 Sanguinaria Canadensis 的生物碱，可通过激活活性氧 (ROS) 的产生来刺激细胞凋亡。Sanguinarine 诱导的细胞凋亡与 JNK 和 NF-κB 的活化有关。[1] |
| Data Literature Source | [1]. Wang Y，Noninvasive bioluminescence imaging of the dynamics of sanguinarine induced apoptosis via activation of reactive oxygen species. Oncotarget. 2016 Apr 19;7(16):22355-67. |
| Unit | Bottle |
| Specification | 5mg 10mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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