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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > DNA Damage & DNA Repai > Sodium ButyrateCAS：156-54-7
Molecular Formula：C4H7NaO2
Molecular Weight：110.09
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：White to off-white Solid
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| CAS | 156-54-7 |
| Name | Sodium Butyrate |
| Molecular Formula | C4H7NaO2 |
| Molecular Weight | 110.09 |
| Solubility | Soluble in Water ≥100mg/mL |
| Purity | ≥98% |
| Appearance | White to off-white Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| EC | EINECS 205-857-6 |
| MDL | MFCD00002816 |
| SMILES | CCCC([O-])=O.[Na+] |
| InChIKey | MFBOGIVSZKQAPD-UHFFFAOYSA-M |
| InChI | InChI=1S/C4H8O2.Na/c1-2-3-4(5)6;/h2-3H2,1H3,(H,5,6);/q;+1/p-1 |
| PubChem CID | 5222465 |
| Target Point | HDAC |
| Passage | DNA Damage/DNA Repair;Epigenetics;NF-κB |
| Background | Sodium Butyrate is a short-chain fatty acid that inhibits histone deacetylases. |
| Biological Activity | Sodium Butyrate是一种短链脂肪酸，可以抑制组蛋白去乙酰化酶。[1-5] |
| Data Literature Source | [1]. Huang W，et al. Inhibition of store-operated Ca2+ entry counteracts the apoptosis of nasopharyngeal carcinoma cells induced by sodium butyrate. Oncol Lett. 2017 Feb;13(2):921-929 [2]. Jaworska J，et al. The potential neuroprotective role of a histone deacetylase inhibitor，sodium butyrate，after neonatal hypoxia-ischemia. J Neuroinflammation. 2017 Feb 10;14(1):34 [3]. Qiu Y，et al. Effect of sodium butyrate on cell proliferation and cell cycle in porcine intestinal epithelial (IPEC-J2) cells. In Vitro Cell Dev Biol Anim. 2017 Jan 27 [4]. Jung HY，et al. Sirtuin-2 inhibition affects hippocampal functions and sodium butyrate ameliorates the reduction in novel object memory，cell proliferation，and neuroblast differentiation. Lab Anim Res. 2016 Dec;32(4):224-230 [5]. Wang P，et al. Sodium butyrate triggers a functional elongation of microglial process via Akt-small RhoGTPase activation and HDACs inhibition. Neurobiol Dis. 2017 Dec 14;111:12-25. |
| Unit | Bottle |
| Specification | 100mg 10mM*1mL in Water 500mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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