{{cart_num}}
My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Others > DigitoninCAS：11024-24-1
Molecular Formula：C56H92O29
Molecular Weight：1229.31
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：HPLC≥50%
Appearance：White to yellow Solid
Qty：
Size：
| CAS | 11024-24-1 |
| Name | Digitonin |
| Molecular Formula | C56H92O29 |
| Molecular Weight | 1229.31 |
| Solubility | Soluble in Water/DMSO ≥20mg/mL |
| Purity | HPLC≥50% |
| Appearance | White to yellow Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| EC | EINECS 234-255-6 |
| MDL | MFCD00077729 |
| SMILES | C[C@@]12[C@]([C@@H]3C)([H])[C@](O[C@]34CC[C@@H](C)CO4)([H])[C@@H](O)[C@@]1([H])[C@@](CC[C@]5([H])[C@@]6(C[C@@H](O)[C@H](O[C@]([C@@H]([C@@H](O)[C@H]7O[C@@](O[C@H](CO)[C@@H](O)[C@@H]8O[C@@](OC[C@@H](O)[C@@H]9O)([H])[C@@H]9O)([H])[C@@H]8O[C@@](O[C@H](CO)[C@H](O)[C@@H]%10O[C@]([C@@H]([C@@H](O)[C@@H]%11O)O)([H])O[C@@H]%11CO)([H])[C@@H]%10O)O)([H])O[C@@H]7CO)C5)C)([H])[C@]6([H])CC2 |
| InChIKey | UVYVLBIGDKGWPX-KUAJCENISA-N |
| InChI | InChI=1S/C56H92O29/c1-19-7-10-56(75-17-19)20(2)31-45(85-56)37(67)32-22-6-5-21-11-26(24(61)12-55(21,4)23(22)8-9-54(31,32)3)76-50-42(72)39(69)44(30(16-60)80-50)81-53-48(47(36(66)29(15-59)79-53)83-49-40(70)33(63)25(62)18-74-49)84-52-43(73)46(35(65)28(14-58)78-52)82-51-41(71)38(68)34(64)27(13-57)77-51/h19-53,57-73H,5-18H2,1-4H3/t19-,20+,21+,22-,23+,24-,25-,26-,27-,28-,29-,30-,31+,32-,33+,34-,35+,36-,37+,38+,39-,40-,41-,42-,43-,44+,45-,46+,47+,48-,49+,50-,51+,52+,53+,54-,55+,56-/m1/s1 |
| PubChem CID | 6474107 |
| Target Point | Others |
| Passage | Others |
| Background | Digitonin has been reported to increase cell membrane permeability by binding to cholesterol molecules and inhibit tumor growth. |
| Biological Activity | Digitonin可通过与胆固醇分子结合来增加细胞膜的通透性，并能抑制肿瘤生长[1]。 |
| Data Literature Source | [1]. Lindnér PG，et al. Digitonin enhances the efficacy of carboplatin in liver tumour after intra-arterial administration. Cancer Chemother Pharmacol. 1997;40(5):444-8. |
| Unit | Bottle |
| Specification | 20mg 10mM*1mL in DMSO 10mM*1mL in Water 50mg 100mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
Sorry, there is no more information.
Hu Y, et al. Biomed Pharmacother. 2022 Nov;155:113739.
Sorry, there is no more information.
Noncanonical autophagy is a new strategy to inhibit HSV-1 through STING1 activation
Click to check >>Author：Zheng Z，Zhao M，Shan H，Fang D，Jin Z，Tang J，Liu Z，Ho
IF：13.3000
Publish_to：Autophagy
PMID：37471002
Par3 promotes breast cancer invasion and migration through pull tension and protein nanoparticle-induced osmotic pressure
Click to check >>Author：Hu Y; Xie Q; Chen S; Zhao W; Zhao X; Ruan Q; Zheng
IF：7.5000
Publish_to：Biomed Pharmacother
PMID：36179489
Manual Download
