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4-Chloro-DL-phenylalanine

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Cat.No：IC0710 Solarbio

CAS：7424-00-2

Molecular Formula：C₉H₁₀ClNO₂

Molecular Weight：199.63

Storage：Powder:-20℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year

Purity：≥98%

Appearance：White to off-white Solid

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Product Information

CAS	7424-00-2
Name	4-Chloro-DL-phenylalanine
Molecular Formula	C₉H₁₀ClNO₂
Molecular Weight	199.63
Solubility	Soluble in DMSO ≥5mg/mL(Need ultrasonic or Water bath)
Purity	≥98%
Appearance	White to off-white Solid
Storage	Powder:-20℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
EC	EINECS 231-051-9
MDL	MFCD00002601
SMILES	NC(CC1=CC=C(Cl)C=C1)C(O)=O
InChIKey	NIGWMJHCCYYCSF-UHFFFAOYSA-N
InChI	InChI=1S/C9H10ClNO2/c10-7-3-1-6(2-4-7)5-8(11)9(12)13/h1-4,8H,5,11H2,(H,12,13)
PubChem CID	4652
Target Point	Tryptophan Hydroxylase
Passage	Metabolic&Enzyme
Background	Fenclonine is a potent irreversible inhibitor of tryptophan hydroxylase (Trp).
Biological Activity	Fenclonine is a selective and irreversible tryptophan hydroxylase inhibitor， which is a rate-limiting enzyme in the biosynthesis of serotonin. Fenclonine can be used in carcinoid syndrome research[1-3].
Data Literature Source	[1]. M Jouvet. Sleep and serotonin: an unfinished story. Neuropsychopharmacology. 1999 Aug;21(2 Suppl):24S-27S. [2]. A K Sanyal，et al. Prostaglandins: antinociceptive effect of prostaglandin E1 in the rat. Clin Exp Pharmacol Physiol. 1977 May-Jun;4(3):247-55. [3]. Shyamshree S S Manna，et al. Paracetamol potentiates the antidepressant-like and anticompulsive-like effects of fluoxetine. Behav Pharmacol. 2015 Apr;26(3):268-81.
Unit	Bottle
Specification	50mg 10mM*1mL in DMSO 100mg 500mg

Remark：These protocols are for reference only. Solarbio does not independently validate these methods.

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