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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > PI3K/Akt/mTOR > BmL-275CAS：866405-64-3
Molecular Formula：C24H25N5O
Molecular Weight：399.49
Storage：Powder:2-8℃，2 years
Purity：≥98%
Appearance：White to off-white Solid
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| CAS | 866405-64-3 |
| Name | BmL-275 |
| Molecular Formula | C24H25N5O |
| Molecular Weight | 399.49 |
| Solubility | Soluble in DMSO ≥0.1mg/mL(Need ultrasonic) |
| Purity | ≥98% |
| Appearance | White to off-white Solid |
| Storage | Powder:2-8℃，2 years |
| MDL | MFCD08705402 |
| SMILES | C12=C(C3=CC=NC=C3)C=NN1C=C(C4=CC=C(OCCN5CCCCC5)C=C4)C=N2 |
| InChIKey | XHBVYDAKJHETMP-UHFFFAOYSA-N |
| InChI | InChI=1S/C24H25N5O/c1-2-12-28(13-3-1)14-15-30-22-6-4-19(5-7-22)21-16-26-24-23(17-27-29(24)18-21)20-8-10-25-11-9-20/h4-11,16-18H,1-3,12-15H2 |
| PubChem CID | 11524144 |
| Target Point | AMPK |
| Passage | PI3K/Akt/mTOR;Epigenetics |
| Background | It is a potent ATP-competitive and selective AMPK inhibitor. Inhibits the BMP pathway by targeting the type I receptors ALK2, ALK3 and ALK6. |
| Unit | Bottle |
| Specification | 10mg 50mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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Diosgenin alleviates the inflammatory damage and insulin resistance in high glucose?induced podocyte cells via the AMPK/SIRT1/NF?κB signaling pathway
Click to check >>Author：Haoyu Yuan, Huacheng Sui, Saimei Li
IF：2.7510
Publish_to：Experimental and Therapeutic Medicine
PMID：37153902
Diosgenin alleviates the inflammatory damage and insulin resistance in high glucose?induced podocyte cells via the AMPK/SIRT1/NF?κB signaling pathway
Click to check >>Author：Haoyu Yuan; Huacheng Sui; Saimei Li
IF：2.7000
Publish_to：Experimental and Therapeutic Medicine
PMID：37153902
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