RS-1
Cat.No:IR0180 Solarbio
CAS:312756-74-4
Molecular Formula:C20H16Br2N2O3S
Molecular Weight:524.23
Storage:Powder:2-8℃,2 years;Insolvent(Mother Liquid):-20℃,6 months;-80℃,1 year
Purity:≥98%
Appearance:White to off-white Solid
Qty:
Size:
{{cart_num}}
My Cart>
Small Molecule Compounds >
Inhibitors & Antagonists & Agonists >
Cell Cycle >
RS-1CAS:312756-74-4
Molecular Formula:C20H16Br2N2O3S
Molecular Weight:524.23
Storage:Powder:2-8℃,2 years;Insolvent(Mother Liquid):-20℃,6 months;-80℃,1 year
Purity:≥98%
Appearance:White to off-white Solid
Qty:
Size:
CAS | 312756-74-4 |
Name | RS-1 |
Molecular Formula | C20H16Br2N2O3S |
Molecular Weight | 524.23 |
Solubility | Soluble in DMSO |
Purity | ≥98% |
Appearance | White to off-white Solid |
Storage | Powder:2-8℃,2 years;Insolvent(Mother Liquid):-20℃,6 months;-80℃,1 year |
Delivery Time | 1-2 Days |
MDL | MFCD00348720 |
SMILES | O=C(NC1=CC=C(Br)C=C1)C2=CC=C(Br)C(S(=O)(NCC3=CC=CC=C3)=O)=C2 |
InChIKey | SWKAVEUTKGKHSR-UHFFFAOYSA-N |
InChI | InChI=1S/C20H16Br2N2O3S/c21-16-7-9-17(10-8-16)24-20(25)15-6-11-18(22)19(12-15)28(26,27)23-13-14-4-2-1-3-5-14/h1-12,23H,13H2,(H,24,25) |
PubChem CID | 1039737 |
Target Point | RAD51 |
Passage | Cell Cycle;DNA Damage/DNA Repair |
Background | RS-1 is an activator of RAD51 that also enhances CRISPR/Cas9 activity. |
Data Literature Source | [1]. Jayathilaka K,et al. A chemical compound that stimulates the human homologous recombination protein RAD51. Proc Natl Acad Sci U S A. 2008 Oct 14;105(41):15848-53. [2]. Song J,et al. RS-1 enhances CRISPR/Cas9- and TALEN-mediated knock-in efficiency. Nat Commun. 2016 Jan 28;7:10548. |
Unit | Bottle |
Specification | 5mg 10mM*1mL in DMSO 10mg |
Remark:These protocols are for reference only. Solarbio does not independently validate these methods.
Note:
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
Sorry, there is no more information.
Sorry, there is no more information.