| English Name |
Anti-ALDH2 Monoclonal Antibody |
| Chinese Name |
乙醛脱氢酶2抗体 |
| Host |
Mouse |
| Clone Type |
Monoclonal Antibody |
| Subtype |
IgG1 |
| Clone Number |
8D4-D6-D11 |
| Dilution Ratio |
WB 1:500-1000. |
| Target |
ALDH2 |
| Synonyms |
Acetaldehyde dehydrogenase 2, Aldehyde dehydrogenase 2 family (mitochondrial), Aldehyde dehydrogenase 2 family, Aldehyde dehydrogenase mitochondrial, Aldehyde dehydrogenase, mitochondrial, ALDH 2, ALDH class 2, ALDH E2, ALDH-E2, ALDH2_HUMAN, ALDHI, ALDM, Liver mitochondrial ALDH, MGC1806, Mitochondrial aldehyde dehydrogenase 2, MS767, Nucleus encoded mitochondrial aldehyde dehydrogenase 2 |
| Background |
This protein belongs to the aldehyde dehydrogenase family of proteins.Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism.Two major liver isoforms of aldehyde dehydrogenase,cytosolic and mitochondrial,can be distinguished by their electrophoretic mobilities,kinetic properties,and subcellular localizations.Most Caucasians have two major isozymes,while approximately 50% of Orientals have the cytosolic isozyme but not the mitochondrial isozyme.A remarkably higher frequency of acute alcohol intoxication among Orientals than among Caucasians could be related to the absence of a catalytically active form of the mitochondrial isozyme.The increased exposure to acetaldehyde in individuals with the catalytically inactive form may also confer greater susceptibility to many types of cancer.This gene encodes a mitochondrial isoform,which has a low Km for acetaldehydes,and is localized in mitochondrial matrix.Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq,Mar 2011] |
| Swiss Prot |
P05091 |
| Gene ID |
217 |
| Subcellular Location |
Mitochondrion matrix |
| Immunogen |
Recombinant protein of human ALDH2 |
| Calculated MW |
56kDa |
| Purification Method |
Affinity purification |
| Storage Buffer |
PBS with 0.02% sodium azide，0.5% BSA，50% glycerol，pH7.3. |
| Storage |
Store at -20℃. Avoid freeze / thaw cycles. |
| Piece |
Piece |
| Specification |
50ul 100ul |
| Reactivity |
Rat Mouse Monkey Hamster Human |
| Application |
WB |
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