English Name |
Anti-NUP98 Polyclonal Antibody |
Host |
Rabbit |
Clone Type |
Polyclonal Antibody |
Subtype |
IgG |
Dilution Ratio |
WB 1:1000-2000.IF 1:50-200 |
Target |
NUP98 |
Synonyms |
96 kDa nucleoporin, 98 kDa nucleoporin, ADAR2, ADIR2, GLFG-repeat containing nucleoporin, Nuclear pore complex protein Nup96, Nuclear pore complex protein Nup98 Nup96, Nucleoporin 98kD, nucleoporin 98kDa, Nucleoporin Nup96, Nucleoporin Nup98, NUP196, NUP96, Nup98, Nup98-Nup96, NUP98_HUMAN |
Background |
Nuclear pore complexes (NPCs) regulate the transport of macromolecules between the nucleus and cytoplasm, and are composed of many polypeptide subunits, many of which belong to the nucleoporin family. This gene belongs to the nucleoporin gene family and encodes a 186 kDa precursor protein that undergoes autoproteolytic cleavage to generate a 98 kDa nucleoporin and 96 kDa nucleoporin. The 98 kDa nucleoporin contains a Gly-Leu-Phe-Gly (GLGF) repeat domain and participates in many cellular processes, including nuclear import, nuclear export, mitotic progression, and regulation of gene expression. The 96 kDa nucleoporin is a scaffold component of the NPC. Proteolytic cleavage is important for targeting of the proteins to the NPC. Translocations between this gene and many other partner genes have been observed in different leukemias. |
Swiss Prot |
P52948 |
Gene ID |
4928 |
Subcellular Location |
Nucleoplasmic side Nucleus Nucleus membrane Peripheral membrane protein nuclear pore complex |
Immunogen |
Recombinant protein of human NUP98 |
Public Immunogen Range |
621-920aa |
Calculated MW |
198/187/98kDa |
Purification Method |
Affinity purification |
Storage Buffer |
PBS with 0.02% sodium azide,50% glycerol,pH7.3. |
Storage |
Store at -20℃. Avoid freeze/thaw cycles. |
Piece |
Piece |
Specification |
50ul 100ul |
Reactivity |
Human Mouse |
Application |
IF WB |