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My CartReactivity：Mouse,Rat,Human
Application：WB,IF
Clone Type：Polyclonal Antibody
Storage：Store at -20℃. Avoid freeze/thaw cycles.
Gene ID：6390
Host：Rabbit
Qty：
Size：
| Name | Anti-SDHB Polyclonal Antibody |
| Host | Rabbit |
| Clone Type | Polyclonal Antibody |
| Subtype | IgG |
| Dilution Ratio | WB 1:100-500. IF 1:50-200 |
| Target | SDHB |
| Background | Complex II of the respiratory chain, which is specifically involved in the oxidation of succinate, carries electrons from FADH to CoQ. The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane. The iron-sulfur subunit is highly conserved and contains three cysteine-rich clusters which may comprise the iron-sulfur centers of the enzyme. Sporadic and familial mutations in this gene result in paragangliomas and pheochromocytoma, and support a link between mitochondrial dysfunction and tumorigenesis. |
| Swiss Prot | P21912 |
| Gene ID | 6390 |
| Subcellular Location | Cytoplasm Cell membrane |
| Immunogen | Recombinant protein of human SDHB |
| Public Immunogen Range | 29-280aa |
| Calculated MW | 32kDa |
| Purification Method | Affinity purification |
| Storage Buffer | PBS with 0.02% sodium azide，50% glycerol，pH7.3. |
| Storage | Store at -20℃. Avoid freeze/thaw cycles. |
| Unit | Piece |
| Specification | 50ul 100ul |
| Reactivity | Mouse Rat Human |
| Application | WB IF |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Kindly reminder：Quick spin before use. If you have any questions, please contact us.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
Western blot analysis with SDHB antibody diluted at 1:1000
Immunofluorescence analysis of U2OS cells using SDHB antibody diluted at 1:100.
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H2S-Activated Ion-Interference Therapy: A Novel Tumor Targeted Therapy Based on Copper-Overload-Mediated Cuproptosis and Pyroptosis
Click to check >>Author：Fan Zhao, Liying Liang, Heng Wang, Chen Wang, Dan Su, Yao Ying, Wangchang Li, Juan Li, Jingwu Zheng, Liang Qiao, Xiaozhou Mou, Shenglei Che, Jing Yu
IF：19.0000
Publish_to：ADVANCED FUNCTIONAL MATERIALS
PMID：
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