English Name |
Anti-COX6A1 Polyclonal Antibody |
Chinese Name |
细胞色素C氧化酶蛋白6A1抗体 |
Host |
Rabbit |
Clone Type |
Polyclonal Antibody |
Subtype |
IgG |
Dilution Ratio |
WB 1:200-2000.IHC 1:20-200.IF 1:50-200 |
Target |
COX6A1 |
Synonyms |
COX VIa L, COX VIa-L, COX6A, COX6A1, COX6AL, CX6A1_HUMAN, Cytochrome c oxidase polypeptide VIa liver, Cytochrome c oxidase polypeptide VIa-liver, Cytochrome c oxidase subunit 6A1, Cytochrome c oxidase subunit 6A1 mitochondrial, Cytochrome C oxidase subunit VIa homolog, Cytochrome c oxidase subunit VIA liver, Cytochrome c oxidase subunit VIa polypeptide 1, Cytochrome c oxidase subunit VIA-liver, MGC104500, mitochondrial |
Background |
Cytochrome c oxidase (COX), the terminal enzyme of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. It is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in the electron transfer and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes polypeptide 1 (liver isoform) of subunit VIa, and polypeptide 1 is found in all non-muscle tissues. Polypeptide 2 (heart/muscle isoform) of subunit VIa is encoded by a different gene, and is present only in striated muscles. These two polypeptides share 66% amino acid sequence identity. It has been reported that there may be several pseudogenes on chromosomes 1, 6, 7q21, 7q31-32 and 12. However, only one pseudogene (COX6A1P) on chromosome 1p31.1 has been documented. |
Swiss Prot |
P12074 |
Gene ID |
1337 |
Subcellular Location |
Mitochondrion inner membrane |
Immunogen |
Recombinant protein of human COX6A1 |
Public Immunogen Range |
25-109aa |
Calculated MW |
12kDa |
Purification Method |
Affinity purification |
Storage Buffer |
PBS with 0.02% sodium azide,50% glycerol,pH7.3. |
Storage |
Store at -20℃. Avoid freeze/thaw cycles. |
Piece |
Piece |
Specification |
50ul 100ul |
Reactivity |
Mouse Rat Human |
Application |
IF IHC WB |