English Name |
Anti-SDCBP Polyclonal Antibody |
Chinese Name |
多配体聚糖结合蛋白1抗体 |
Host |
Rabbit |
Clone Type |
Polyclonal Antibody |
Subtype |
IgG |
Dilution Ratio |
WB 1:500-2000. IF 1:50-200. |
Target |
SDCBP |
Synonyms |
MDA-9, MDA9, Melanoma differentiation-associated protein 9, Pro-TGF-alpha cytoplasmic domain-interacting protein 18, Scaffold protein Pbp1, SDCB1_HUMAN, SDCBP, ST1, SYCL, Syndecan binding protein (syntenin), Syndecan binding protein 1, Syndecan-binding protein 1, Syntenin 1, Syntenin-1, TACIP18 |
Background |
The protein encoded by this gene was initially identified as a molecule linking syndecan-mediated signaling to the cytoskeleton. The syntenin protein contains tandemly repeated PDZ domains that bind the cytoplasmic, C-terminal domains of a variety of transmembrane proteins. This protein may also affect cytoskeletal-membrane organization, cell adhesion, protein trafficking, and the activation of transcription factors. The protein is primarily localized to membrane-associated adherens junctions and focal adhesions but is also found at the endoplasmic reticulum and nucleus. Alternative splicing results in multiple transcript variants encoding different isoforms. Related pseudogenes have been identified on multiple chromosomes. |
Swiss Prot |
O00560 |
Gene ID |
6386 |
Subcellular Location |
Cell junction Cell membrane Cytoplasm Endoplasmic reticulum membrane Melanosome Nucleus Peripheral membrane protein adherens junction cytoskeleton cytosol focal adhesion |
Immunogen |
Recombinant protein of human SDCBP |
Public Immunogen Range |
1-260aa |
Calculated MW |
32kDa |
Purification Method |
Affinity purification |
Storage Buffer |
PBS with 0.02% sodium azide,50% glycerol,pH7.3. |
Storage |
Store at -20℃. Avoid freeze/thaw cycles. |
Piece |
Piece |
Specification |
50ul 100ul |
Reactivity |
Human |
Application |
IF WB |