English Name |
Anti-KLC1 Polyclonal Antibody |
Chinese Name |
驱动蛋白轻链1抗体 |
Host |
Rabbit |
Clone Type |
Polyclonal Antibody |
Subtype |
IgG |
Dilution Ratio |
WB 1:500-2000.IHC 1:50-200 |
Target |
KLC1 |
Synonyms |
KLC,KNS2,KNS2A,Kinesin 2 60/70kDa, Kinesin light chain 1, Kinesin2, KLC 1, KLC, Klc1, KLC1_HUMAN, KNS 2, KNS 2A, KNS2, KNS2A, Medulloblastoma antigen MU MB 2.50, MGC15245 |
Background |
Conventional kinesin is a tetrameric molecule composed of two heavy chains and two light chains, and transports various cargos along microtubules toward their plus ends. The heavy chains provide the motor activity, while the light chains bind to various cargos. This gene encodes a member of the kinesin light chain family. It associates with kinesin heavy chain through an N-terminal domain, and six tetratricopeptide repeat (TPR) motifs are thought to be involved in binding of cargos such as vesicles, mitochondria, and the Golgi complex. Thus, kinesin light chains function as adapter molecules and not motors per se. Although previously named 'kinesin 2', this gene is not a member of the kinesin-2 / kinesin heavy chain subfamily of kinesin motor proteins. Extensive alternative splicing produces isoforms with different C-termini that are proposed to bind to different cargos; however, the full-length nature and/or biological validity of most of these variants have not been determined. |
Swiss Prot |
Q07866 |
Gene ID |
3831 |
Subcellular Location |
Cell projection Cytoplasm Cytoplasmic vesicle cytoskeleton growth cone |
Immunogen |
Recombinant protein of human KLC1 |
Public Immunogen Range |
261-560aa |
Calculated MW |
65kDa |
Purification Method |
Affinity purification |
Storage Buffer |
PBS with 0.02% sodium azide,50% glycerol,pH7.3. |
Storage |
Store at -20℃. Avoid freeze / thaw cycles. |
Piece |
Piece |
Specification |
50ul 100ul |
Reactivity |
Rat Human Mouse |
Application |
IHC WB |