English Name |
Anti-ATAD3A Polyclonal Antibody |
Chinese Name |
三磷酸腺苷酶家族蛋白3A抗体 |
Host |
Rabbit |
Clone Type |
Polyclonal Antibody |
Subtype |
IgG |
Dilution Ratio |
WB 1:100-500. IHC 1:100-200. |
Target |
ATAD3A |
Synonyms |
AAA-ATPase TOB3, ATAD3B, ATAD3C, Atad3a, ATPase family AAA domain containing protein 3A, ATPase family AAA domain-containing protein 3, ATPase family, AAA domain containing 3A, FLJ10709, FLJ35514, AAA ATPase TOB3, AAA-TOB3, ATPase family AAA domain containing protein 3B, ATPase family, AAA domain containing 3B, ATPase family, AAA domain containing, member 3B, TOB3, ATD3A_HUMAN, ATAD3A/B/C |
Background |
This gene encodes a ubiquitously expressed mitochondrial membrane protein that contributes to mitochondrial dynamics, nucleoid organization, protein translation, cell growth, and cholesterol metabolism. This gene is a member of the ATPase family AAA-domain containing 3 gene family which, in humans, includes two other paralogs. Naturally occurring mutations in this gene are associated with distinct neurological syndromes including Harel-Yoon syndrome. High-level expression of this gene is associated with poor survival in breast cancer patients. A homozygous knockout of the orthologous gene in mice results in embryonic lethality at day 7.5 due to growth retardation and defective development of the trophoblast lineage. Alternative splicing results in multiple transcript variants. |
Swiss Prot |
Q9NVI7 |
Gene ID |
55210 |
Subcellular Location |
Mitochondrion inner membrane Mitochondrion matrix Single-pass membrane protein mitochondrion nucleoid |
Immunogen |
Recombinant protein of human ATAD3A |
Public Immunogen Range |
1-240aa |
Calculated MW |
71kDa |
Purification Method |
Affinity purification |
Storage Buffer |
PBS with 0.02% sodium azide,50% glycerol,pH7.3. |
Storage |
Store at -20℃. Avoid freeze/thaw cycles. |
Piece |
Piece |
Specification |
50ul 100ul |
Reactivity |
Human Mouse |
Application |
IHC WB |