English Name |
Anti-COX7A2L Polyclonal Antibody |
Chinese Name |
细胞色素c氧化酶亚基7A相关蛋白抗体 |
Host |
Rabbit |
Clone Type |
Polyclonal Antibody |
Subtype |
IgG |
Dilution Ratio |
WB 1:500-1000. |
Target |
COX7A2L |
Synonyms |
COX7a related protein, COX7a-related protein, COX7A2L, COX7AR, COX7R_HUMAN, COX7RP, Cytochrome c oxidase subunit 7A-related protein, cytochrome c oxidase subunit 7A-related protein, mitochondrial, cytochrome c oxidase subunit VII-related protein, cytochrome c oxidase subunit VIIa polypeptide 2 like, Cytochrome c oxidase subunit VIIa related protein, mitochondrial, Cytochrome c oxidase subunit VIIa-related protein, EB1, Estrogen receptor binding CpG island, mitochondrial, SIG81 |
Background |
Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes a protein similar to polypeptides 1 and 2 of subunit VIIa in the C-terminal region, and also highly similar to the mouse Sig81 protein sequence. This gene is expressed in all tissues, and upregulated in a breast cancer cell line after estrogen treatment. It is possible that this gene represents a regulatory subunit of COX and mediates the higher level of energy production in target cells by estrogen. Several transcript variants, some protein-coding and others non-protein coding, have been found for this gene. |
Swiss Prot |
O14548 |
Gene ID |
9167 |
Subcellular Location |
Mitochondrion inner membrane |
Immunogen |
Recombinant protein of human COX7A2L |
Public Immunogen Range |
1-114aa |
Calculated MW |
13kDa |
Purification Method |
Affinity purification |
Storage Buffer |
PBS with 0.02% sodium azide,50% glycerol,pH7.3. |
Storage |
Store at -20℃. Avoid freeze/thaw cycles. |
Piece |
Piece |
Specification |
50ul 100ul |
Reactivity |
Rat Mouse Human |
Application |
WB |