English Name |
Anti-XPC Polyclonal Antibody |
Chinese Name |
DNA补充修复XPC细胞蛋白抗体 |
Host |
Rabbit |
Clone Type |
Polyclonal Antibody |
Subtype |
IgG |
Dilution Ratio |
WB 1:500-2000. IHC 1:50-200. IP 0.5μg-4μg. |
Target |
XPC |
Synonyms |
Xeroderma pigmentosum complementation group C, DNA repair protein complementing XP C cells, DNA repair protein complementing XP-C cells, DNA repair protein complementing XPC cells, p125, RAD4, Xeroderma pigmentosum group C complementing protein, Xeroderma pigmentosum group C protein, Xeroderma pigmentosum group C-complementing protein, Xeroderma pigmentosum group III, XP 3, XP C, XP group C, XP3, Xpc, XPC gene, XPC_HUMAN, XPCC |
Background |
This gene encodes a component of the nucleotide excision repair (NER) pathway. There are multiple components involved in the NER pathway, including Xeroderma pigmentosum (XP) A-G and V, Cockayne syndrome (CS) A and B, and trichothiodystrophy (TTD) group A, etc. This component, XPC, plays an important role in the early steps of global genome NER, especially in damage recognition, open complex formation, and repair protein complex formation. Mutations in this gene or some other NER components result in Xeroderma pigmentosum, a rare autosomal recessive disorder characterized by increased sensitivity to sunlight with the development of carcinomas at an early age. Alternatively spliced transcript variants have been found for this gene. |
Swiss Prot |
Q01831 |
Gene ID |
7508 |
Subcellular Location |
Cytoplasm Nucleus |
Immunogen |
Recombinant protein of human XPC |
Public Immunogen Range |
700-940aa |
Calculated MW |
102/16kDa |
Purification Method |
Affinity purification |
Storage Buffer |
PBS with 0.02% sodium azide,50% glycerol,pH7.3. |
Storage |
Store at -20℃. Avoid freeze/thaw cycles. |
Piece |
Piece |
Specification |
50ul 100ul |
Reactivity |
Human |
Application |
IP IHC WB |