English Name |
Anti-EPHB2 Polyclonal Antibody |
Chinese Name |
酪氨酸蛋白激酶受体B2抗体 |
Host |
Rabbit |
Clone Type |
Polyclonal Antibody |
Subtype |
IgG |
Dilution Ratio |
WB 1:500-2000. IHC 1:50-200. |
Target |
EPHB2 |
Synonyms |
Eph receptor B2, Developmentally regulated EPH related tyrosine kinase, DRT, ELK related protein tyrosine kinase, EPH tyrosine kinase 3, EphB2, Ephrin type B receptor 2, EPHT 3, ERK, ETECK, Nuk, Prkm 5, Receptor protein tyrosine kinase HEK 5, Sek 3, Tyro 5, Tyrosine protein kinase receptor CEK 5, Tyrosine protein kinase receptor EPH 3, Tyrosine protein kinase receptor QEK 5, EPHB2_HUMAN |
Background |
This gene encodes a member of the Eph receptor family of receptor tyrosine kinase transmembrane glycoproteins. These receptors are composed of an N-terminal glycosylated ligand-binding domain, a transmembrane region and an intracellular kinase domain. They bind ligands called ephrins and are involved in diverse cellular processes including motility, division, and differentiation. A distinguishing characteristic of Eph-ephrin signaling is that both receptors and ligands are competent to transduce a signaling cascade, resulting in bidirectional signaling. This protein belongs to a subgroup of the Eph receptors called EphB. Proteins of this subgroup are distinguished from other members of the family by sequence homology and preferential binding affinity for membrane-bound ephrin-B ligands. Allelic variants are associated with prostate and brain cancer susceptibility. Alternative splicing results in multiple transcript variants. |
Swiss Prot |
P29323 |
Gene ID |
2048 |
Subcellular Location |
Cell membrane Cell projection Single-pass type I membrane protein axon dendrite |
Immunogen |
Recombinant protein of human EPHB2 |
Public Immunogen Range |
250-540aa |
Calculated MW |
117kDa |
Purification Method |
Affinity purification |
Storage Buffer |
PBS with 0.02% sodium azide,50% glycerol,pH7.3. |
Storage |
Store at -20℃. Avoid freeze/thaw cycles. |
Piece |
Piece |
Y-Dilution Ratio |
"WB 1:500-2000." |
Specification |
50ul 100ul |
Reactivity |
Mouse Human |
Application |
WB |