English Name |
Anti-Phospho-RPS6-S240/244 Polyclonal Antibody |
Chinese Name |
核糖体蛋白S6抗体 |
Host |
Rabbit |
Clone Type |
Polyclonal Antibody |
Subtype |
IgG |
Dilution Ratio |
WB 1:500-2000. IHC 1:50-200. IP 0.5μg-4μg. |
Target |
Phospho-RPS6-S240/244 |
Synonyms |
RPS6 (phospho S240 + S244), p-RPS6 (phospho S240 + S244), Air8, DS6, Hemocytes enlarged, Hen, L(1)AIR8, Lethal (1) haemocytes enlarged, Lethal aberrant immune response 8, Lethal(1)abberant immune response[8], Phosphoprotein NP33, Pp30, Ribosomal protein S6, RP S6, RPS 6, RpS6, RS6, RS6_HUMAN, S6, S6 Ribosomal Protein |
Background |
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a cytoplasmic ribosomal protein that is a component of the 40S subunit. The protein belongs to the S6E family of ribosomal proteins. It is the major substrate of protein kinases in the ribosome, with subsets of five C-terminal serine residues phosphorylated by different protein kinases. Phosphorylation is induced by a wide range of stimuli, including growth factors, tumor-promoting agents, and mitogens. Dephosphorylation occurs at growth arrest. The protein may contribute to the control of cell growth and proliferation through the selective translation of particular classes of mRNA. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. |
Swiss Prot |
P62753 |
Gene ID |
6194 |
Subcellular Location |
Cytosol Endoplasmic reticulum Nucleus |
Immunogen |
A phospho specific peptide corresponding to residues surrounding S240/244 of human RPS6 |
Calculated MW |
29kDa |
Purification Method |
Affinity purification |
Storage Buffer |
PBS with 0.02% sodium azide,50% glycerol,pH7.3. |
Storage |
Store at -20℃. Avoid freeze/thaw cycles. |
Piece |
Piece |
Specification |
50ul 100ul |
Reactivity |
Rat Human Mouse |
Application |
IP IHC WB |