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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Others > NaringeninCAS：480-41-1
Molecular Formula：C15H12O5
Molecular Weight：272.25
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：HPLC≥98%
Appearance：White to yellow Solid
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| CAS | 480-41-1 |
| Name | Naringenin |
| Molecular Formula | C15H12O5 |
| Molecular Weight | 272.25 |
| Solubility | Soluble in DMSO ≥5mg/mL;Soluble in Ethanol ≥10mg/mL;Soluble in Water ＜1mg/mL |
| Purity | HPLC≥98% |
| Appearance | White to yellow Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| EC | EINECS 266-769-1 |
| MDL | MFCD00006844 |
| SMILES | O=C1C[C@@H](C2=CC=C(O)C=C2)OC3=CC(O)=CC(O)=C13 |
| InChIKey | FTVWIRXFELQLPI-ZDUSSCGKSA-N |
| InChI | InChI=1S/C15H12O5/c16-9-3-1-8(2-4-9)13-7-12(19)15-11(18)5-10(17)6-14(15)20-13/h1-6,13,16-18H,7H2/t13-/m0/s1 |
| PubChem CID | 439246 |
| Target Point | Others |
| Passage | Others |
| Background | Naringenin is a flavanone with anti-inflammatory and antioxidant activities, which can be used for antioxidant, free radical scavengers, anti-inflammatory agents, carbohydrate metabolism promoters, immune system modulators and other related research. |
| Biological Activity | Naringenin是葡萄柚中主要的黄烷酮; 显示出强烈的抗炎和抗氧化活性。[1-5] |
| Data Literature Source | [1]. Arul D， et al. Naringenin (citrus flavonone) induces growth inhibition， cell cycle arrest and apoptosis in human hepatocellular carcinoma cells. Pathol Oncol Res. 2013 Oct; 19 (4) :763-70. [2]. Ahamad MS， et al. Induction of apoptosis and antiproliferative activity of naringenin in human epidermoid carcinomacell through ROS generation and cell cycle arrest. PLoS One. 2014 Oct 16; 9 (10) :e110003. [3]. Cho KW， et al. Dietary naringenin increases hepatic peroxisome proliferators-activated receptor α proteinexpression and decreases plasma triglyceride and adiposity in rats. Eur J Nutr. 2011 Mar; 50 (2) :81-8. [4]. Mulvihill EE， et al. Naringenin prevents dyslipidemia， apolipoprotein B overproduction， and hyperinsulinemia in LDLreceptor-null mice with diet-induced insulin resistance. Diabetes. 2009 Oct; 58 (10) :2198-210. [5]. Chen S， et al. Naringenin inhibits TNF-α induced VSMC proliferation and migration via induction of HO-1. Food Chem Toxicol. 2012 Sep; 50 (9) :3025-31 |
| Unit | Bottle |
| Specification | 20mg 10mM*1mL in DMSO 50mg 100mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Note：
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3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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