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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Endocrinology & Hormones > IloprostCAS：78919-13-8
Molecular Formula：C22H32O4
Molecular Weight：360.49
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：HPLC≥98%
Appearance：Solid
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| CAS | 78919-13-8 |
| Name | Iloprost |
| Molecular Formula | C22H32O4 |
| Molecular Weight | 360.49 |
| Solubility | Soluble in DMSO |
| Purity | HPLC≥98% |
| Appearance | Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| MDL | MFCD00867145 |
| SMILES | O=C(O)CCC/C=C1C[C@@]2([H])C[C@@H](O)[C@H](/C=C/[C@@H](O)C(C)CC#CC)[C@@]2([H])C\1 |
| InChIKey | HIFJCPQKFCZDDL-ACWOEMLNSA-N |
| InChI | InChI=1S/C22H32O4/c1-3-4-7-15(2)20(23)11-10-18-19-13-16(8-5-6-9-22(25)26)12-17(19)14-21(18)24/h8,10-11,15,17-21,23-24H,5-7,9,12-14H2,1-2H3,(H,25,26)/b11-10+,16-8+/t15?,17-,18+,19-,20+,21+/m0/s1 |
| PubChem CID | 5311181 |
| Target Point | Prostaglandin Receptor |
| Passage | Endocrinology & Hormones;GPCR & G Protein |
| Background | It is a stable prostacyclin analog. |
| Biological Activity | Iloprost (ZK 36374; Ciloprost) is a prostacyclin (PGI2) analogue， involves in embryo development and inflammation improvement， and inhibits tumor metastasis. Iloprost can be used for peripheral vascular research[1][2][3][4]. |
| IC50 | IP |
| Data Literature Source | [1]. Kowalczyk-Zieba I，et al. Iloprost affects in vitro maturation and developmental competence of bovine oocytes. Theriogenology. 2020 Nov;157:286-296. [2]. Hildebrand M. Pharmacokinetics of iloprost and cicaprost in mice. Prostaglandins. 1992 Nov;44(5):431-42. [3]. Olave N，et al. Iloprost attenuates hyperoxia-mediated impairment of lung development in newborn mice. Am J Physiol Lung Cell Mol Physiol. 2018 Oct 1;315(4):L535-L544. [4]. Schneider MR，et al. Effects of prostacyclin analogues in in vivo tumor models. Adv Prostaglandin Thromboxane Leukot Res. 1991;21B:901-8. |
| Unit | Bottle |
| Specification | 1mg 5mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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