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Polyphyllin I

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Cat.No：IP0600 Solarbio

CAS：50773-41-6

Molecular Formula：C₄₄H₇₀O₁₆

Molecular Weight：855.02

Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year

Purity：HPLC≥98%

Appearance：White to off-white Solid

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Product Information

CAS	50773-41-6
Name	Polyphyllin I
Molecular Formula	C₄₄H₇₀O₁₆
Molecular Weight	855.02
Solubility	Soluble in DMSO
Purity	HPLC≥98%
Appearance	White to off-white Solid
Storage	Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
MDL	MFCD13195305
SMILES	C[C@H](CC1)CO[C@]21O[C@@]3([H])C[C@@]4([H])[C@@]5([H])[C@]([C@](CC[C@H](O[C@]6([H])O[C@H](CO)[C@@H](O[C@]7([H])O[C@@H](CO)[C@H](O)[C@H]7O)[C@H](O)[C@H]6O[C@@]8([H])[C@H](O)[C@H](O)[C@@H](O)[C@H](C)O8)C9)(C)C9=CC5)([H])CC[C@]4(C)[C@@]3([H])[C@@H]2C
InChIKey	LRRDDWMXYOSKIC-IPKCVOQPSA-N
InChI	InChI=1S/C44H70O16/c1-19-8-13-44(53-18-19)20(2)30-27(60-44)15-26-24-7-6-22-14-23(9-11-42(22,4)25(24)10-12-43(26,30)5)55-41-38(59-39-35(51)33(49)31(47)21(3)54-39)36(52)37(29(17-46)57-41)58-40-34(50)32(48)28(16-45)56-40/h6,19-21,23-41,45-52H,7-18H2,1-5H3/t19-,20+,21+,23+,24-,25+,26+,27+,28+,29-,30+,31+,32+,33-,34-,35-,36+,37-,38-,39+,40+,41-,42+,43+,44-/m1/s1
PubChem CID	11018329
Target Point	JNK
Passage	MAPK
Background	Polyphyllin I, a bioactive component of Paris polyphylla, is an activator of JNK signaling and an inhibitor of PDK1/Akt/mTOR signaling, which induces autophagy, G2/M phase arrest and apoptosis.
Unit	Bottle
Specification	5mg

Remark：These protocols are for reference only. Solarbio does not independently validate these methods.

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