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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Others > BetulinCAS：473-98-3
Molecular Formula：C30H50O2
Molecular Weight：442.72
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：HPLC≥98%
Appearance：White to off-white Solid
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| CAS | 473-98-3 |
| Name | Betulin |
| Molecular Formula | C30H50O2 |
| Molecular Weight | 442.72 |
| Solubility | Soluble in DMSO ≥3mg/mL |
| Purity | HPLC≥98% |
| Appearance | White to off-white Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| EC | EINECS 207-475-5 |
| MDL | MFCD00016802 |
| SMILES | C=C(C)[C@@H]1CC[C@]2(CO)CC[C@@]3(C)[C@]4(C)CC[C@@]5([H])C(C)(C)[C@@H](O)CC[C@]5(C)[C@@]4([H])CC[C@]3([H])[C@]21[H] |
| InChIKey | FVWJYYTZTCVBKE-ROUWMTJPSA-N |
| InChI | InChI=1S/C30H50O2/c1-19(2)20-10-15-30(18-31)17-16-28(6)21(25(20)30)8-9-23-27(5)13-12-24(32)26(3,4)22(27)11-14-29(23,28)7/h20-25,31-32H,1,8-18H2,2-7H3/t20-,21+,22-,23+,24-,25+,27-,28+,29+,30+/m0/s1 |
| PubChem CID | 72326 |
| Target Point | SREBP |
| Passage | Others |
| Background | Betulin is an SREBP inhibitor. |
| Biological Activity | Betulin是一种SREBP抑制剂，在K562细胞中的IC50值是14.5 μM[1-3]。 |
| Data Literature Source | [1]. Król SK，et al. Comprehensive review on betulin as a potent anticancer agent. Biomed Res Int. 2015;2015:584189. [2]. Drag M，et al. Comparision of the Cytotoxic Effects of Birch Bark Extract，Betulin and Betulinic Acid Towards Human Gastric Carcinoma and Pancreatic Carcinoma Drug-sensitive and Drug-Resistant Cell Lines. Molecules. 2009 Apr 24;14(4):1639-51. [3]. Ma C，et al. Protective effect of betulin on cognitive decline in streptozotocin (STZ)-induced diabetic rats. Neurotoxicology. 2016 Dec;57:104-111 |
| Unit | Bottle |
| Specification | 10mg 20mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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